Cell Biology Antibodies 4

Anti-STX10 Antibody (CAB13827)

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SKU:
CAB13827
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-STX10 Antibody
Antibody SKU:CAB13827
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 76-165 of human STX10 (NP_001258540.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:HeLa
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 76-165 of human STX10 (NP_001258540.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GKPA AQKS PSDL LDAS AVSA TSRY IEEQ QATQ QLIM DEQD QQLE MVSG SIQV LKHM SGRV GEEL DEQG IMLD AFAQ EMDH TQSR MDGV LR
Gene ID:8677
Uniprot:O60499
Cellular Location:Golgi apparatus membrane, Single-pass type IV membrane protein
Calculated MW:22kDa/28kDa
Observed MW:35kDa
Synonyms:STX10, SYN10, hsyn10
Background:This gene belongs to the syntaxin family and encodes a soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE). The encoded protein is involved in docking and fusion events at the Golgi apparatus. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:STX10: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. Belongs to the syntaxin family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral; Vesicle

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: integral to membrane; perinuclear region of cytoplasm; SNARE complex; trans-Golgi network; trans-Golgi network membrane; vesicle

Molecular Function:protein binding; SNAP receptor activity; syntaxin binding

Biological Process: intracellular protein transport; regulation of protein localization; retrograde transport, endosome to Golgi; vesicle docking; vesicle fusion

NCBI Summary:This gene belongs to the syntaxin family and encodes a soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE). The encoded protein is involved in docking and fusion events at the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
UniProt Code:O60499
NCBI GenInfo Identifier:17368024
NCBI Gene ID:8677
NCBI Accession:O60499.1
UniProt Secondary Accession:O60499,Q6IAP4, Q96AE8, A6NC41,
UniProt Related Accession:O60499
Molecular Weight:22,445 Da
NCBI Full Name:Syntaxin-10
NCBI Synonym Full Names:syntaxin 10
NCBI Official Symbol:STX10  
NCBI Official Synonym Symbols:SYN10; hsyn10  
NCBI Protein Information:syntaxin-10
UniProt Protein Name:Syntaxin-10
Protein Family:Syntaxin
UniProt Gene Name:STX10  
UniProt Entry Name:STX10_HUMAN
Anti-STX10 Antibody (CAB13827)Western blot analysis of extracts of HeLa cells, using STX10 antibody (CAB13827) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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