Cell Biology Antibodies 10
Anti-STRN3 Antibody (CAB6756)
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- SKU:
- CAB6756
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-STRN3 Antibody |
| Antibody SKU: | CAB6756 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-460 of human STRN3 (NP_001077362.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SH-SY5Y, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-460 of human STRN3 (NP_001077362.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VRSL LGLS NSEP NGSV ETKN LEQI LNGG ESPK QKGQ EIKR SSGD VLET FNFL ENAD DSDE DEEN DMIE GIPE GKDK HRMN KHKI GNEG LAAD LTDD PDTE EALK EFDF LVTA EDGE GAGE ARSS GDGT EWDK DDLS PTAE VWDV DQGL ISKL KEQY KKER KGKK GVKR ANRT KLYD MIAD LGDD ELPH IPSG IINQ SRSA STRM TDHE GARA EEAE PITF PSGG GKSF IMGS DDVL LSVL GLGD LADL TVTN DADY SYDL P |
| Gene ID: | 29966 |
| Uniprot: | Q13033 |
| Cellular Location: | Cytoplasm, Membrane, Peripheral membrane protein |
| Calculated MW: | 77kDa/87kDa |
| Observed MW: | 87kDa |
| Synonyms: | STRN3, PPP2R6B, S/G2NA, SG2NA |
| Background: |
| UniProt Protein Function: | SG2NA: a protein of the WD-repeat striatin family. Mainly expressed within neurons and thought to act both as scaffolds and as Ca(2+)-dependent signalling proteins. May interact with protein phosphatase 2A. Two alternatively spliced isoforms have been described. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Transcription factor; Protein phosphatase, regulatory subunit Chromosomal Location of Human Ortholog: 14q13-q21 Cellular Component: nucleoplasm; Golgi apparatus; protein phosphatase type 2A complex; protein complex; cell soma; cytoplasm; dendrite; plasma membrane; nucleus Molecular Function:calmodulin binding; protein binding; protein phosphatase 2A binding; protein complex binding; transcription factor activity Biological Process: positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; response to estradiol stimulus; negative regulation of estrogen receptor signaling pathway |
| UniProt Code: | Q13033 |
| NCBI GenInfo Identifier: | 223634717 |
| NCBI Gene ID: | 29966 |
| NCBI Accession: | Q13033.3 |
| UniProt Secondary Accession: | Q13033,Q9NRA5, A2RTX7, A6NHZ7, |
| UniProt Related Accession: | Q13033 |
| Molecular Weight: | 797 |
| NCBI Full Name: | Striatin-3 |
| NCBI Synonym Full Names: | striatin, calmodulin binding protein 3 |
| NCBI Official Symbol: | STRN3 |
| NCBI Official Synonym Symbols: | SG2NA |
| NCBI Protein Information: | striatin-3; s/G2 antigen; nuclear autoantigen; cell cycle autoantigen SG2NA; cell cycle S/G2 nuclear autoantigen |
| UniProt Protein Name: | Striatin-3 |
| UniProt Synonym Protein Names: | Cell cycle autoantigen SG2NA; S/G2 antigen |
| Protein Family: | Striatin |
| UniProt Gene Name: | STRN3 |
| UniProt Entry Name: | STRN3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using STRN3 antibody (CAB6756) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 10s. |
 | Immunohistochemistry of paraffin-embedded mouse lung using STRN3 antibody (CAB6756) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat kidney using STRN3 antibody (CAB6756) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using STRN3 antibody (CAB6756) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of HeLa cells using STRN3 antibody (CAB6756). Blue: DAPI for nuclear staining. |
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