Cell Biology Antibodies 11

Anti-STRN Antibody (CAB7734)

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SKU:
CAB7734
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-STRN Antibody
Antibody SKU:CAB7734
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 581-780 of human STRN (NP_003153.2).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:A-549, NIH/3T3, Mouse lung, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 581-780 of human STRN (NP_003153.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:HQRL LSCS ADGT LRLW NTTE VAPA LSVF NDTK ELGI PASV DLVS SDPS HMVA SFSK GYTS IFNM ETQQ RILT LESN VDTT ANSS CQIN RVIS HPTL PISI TAHE DRHI KFYD NNTG KLIH SMVA HLEA VTSL AVDP NGLY LMSG SHDC SIRL WNLE SKTC IQEF TAHR KKFE ESIH DVAF HPSK CYIA SAGA DALA KVFV
Gene ID:6801
Uniprot:O43815
Cellular Location:Cell projection, Cytoplasm, Membrane, Peripheral membrane protein, dendritic spine
Calculated MW:80kDa/86kDa
Observed MW:120kDa
Synonyms:STRN, PPP2R6A, SG2NA, STRN1, striatin
Background:
UniProt Protein Function:STRN: Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling. Belongs to the WD repeat striatin family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Protein phosphatase, regulatory subunit; Adaptor/scaffold; Cell development/differentiation

Chromosomal Location of Human Ortholog: 2p22.2

Cellular Component: postsynaptic membrane; protein phosphatase type 2A complex; tight junction; cell soma; membrane; cytoplasm; postsynaptic density; dendritic spine

Molecular Function:calmodulin binding; protein binding; protein phosphatase 2A binding; protein complex binding; estrogen receptor binding

Biological Process: negative regulation of cell proliferation; Wnt receptor signaling pathway; dendrite development; locomotory behavior

UniProt Code:O43815
NCBI GenInfo Identifier:143933639
NCBI Gene ID:6801
NCBI Accession:O43815.4
UniProt Secondary Accession:O43815,Q3KP65, Q53TQ8, Q9NP38,
UniProt Related Accession:O43815
Molecular Weight:780
NCBI Full Name:Striatin
NCBI Synonym Full Names:striatin, calmodulin binding protein
NCBI Official Symbol:STRN  
NCBI Official Synonym Symbols:SG2NA  
NCBI Protein Information:striatin; striatin, calmodulin-binding protein
UniProt Protein Name:Striatin
Protein Family:Striatin
UniProt Gene Name:STRN  
UniProt Entry Name:STRN_HUMAN
Anti-STRN Antibody (CAB7734)Western blot analysis of extracts of various cell lines, using STRN antibody (CAB7734) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
Anti-STRN Antibody (CAB7734)Immunohistochemistry of paraffin-embedded mouse brain using STRN antibody (CAB7734) at dilution of 1:100 (40x lens).
Anti-STRN Antibody (CAB7734)Immunohistochemistry of paraffin-embedded rat heart using STRN antibody (CAB7734) at dilution of 1:100 (40x lens).
Anti-STRN Antibody (CAB7734)Immunohistochemistry of paraffin-embedded human liver damage using STRN antibody (CAB7734) at dilution of 1:100 (40x lens).
Anti-STRN Antibody (CAB7734)Immunofluorescence analysis of A549 cells using STRN antibody (CAB7734). Blue: DAPI for nuclear staining.
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