Cell Biology Antibodies 14
Anti-STOX1 Antibody (CAB18137)
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- SKU:
- CAB18137
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-STOX1 Antibody |
| Antibody SKU: | CAB18137 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human STOX1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant protein of human STOX1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 219736 |
| Uniprot: | Q6ZVD7 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | C10orf24, STOX1 |
| Background: |
| UniProt Protein Function: | STOX1: Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4); also known as gestational proteinuric hypertension. Preeclampsia is a pregnancy-associated disease with maternal symptoms but placental origin. Unlike most other human disorders, it impacts 2 individuals, the mother and her child, both of whom can be severely affected. The pathological mechanism of PEE4 involves the loss of function of STOX1 in the placenta. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 10q22.1 Cellular Component: cell cortex; centrosome; cytoplasm; nucleolus; nucleoplasm; nucleus Molecular Function:protein binding Biological Process: cell division; inner ear development; mitosis; positive regulation of cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein kinase B signaling cascade; regulation of gene expression; regulation of mitochondrial membrane potential; transcription, DNA-dependent Disease: Preeclampsia/eclampsia 4 |
| NCBI Summary: | The protein encoded by this gene may function as a DNA binding protein. Mutations in this gene are associated with pre-eclampsia/eclampsia 4 (PEE4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| UniProt Code: | Q6ZVD7 |
| NCBI GenInfo Identifier: | 194328687 |
| NCBI Gene ID: | 219736 |
| NCBI Accession: | NP_001123631.1 |
| UniProt Secondary Accession: | Q6ZVD7,Q4F8Q6, Q5I946, Q5I947, Q5I948, Q5VX38, Q5VX39 A2A3Q9, A5D6Y7, B0QZA4, B0QZA5, B0QZA6, |
| UniProt Related Accession: | Q6ZVD7 |
| Molecular Weight: | |
| NCBI Full Name: | storkhead-box protein 1 isoform b |
| NCBI Synonym Full Names: | storkhead box 1 |
| NCBI Official Symbol: | STOX1 |
| NCBI Official Synonym Symbols: | PEE4; C10orf24 |
| NCBI Protein Information: | storkhead-box protein 1 |
| UniProt Protein Name: | Storkhead-box protein 1 |
| UniProt Synonym Protein Names: | Winged-helix domain-containing protein |
| Protein Family: | Storkhead-box protein |
| UniProt Gene Name: | STOX1 |
| UniProt Entry Name: | STOX1_HUMAN |
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