Cell Biology Antibodies 11

Anti-STK19 Antibody (CAB7574)

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SKU:
CAB7574
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-STK19 Antibody
Antibody SKU:CAB7574
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 75-364 of human STK19 (NP_004188.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:SW620, MCF7, Jurkat, HepG2, Mouse intestine, Mouse testis, Mouse liver, Rat lung, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 75-364 of human STK19 (NP_004188.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GTPG ETVR HCSA PEDP IFRF SSLH SYPF PGTI KSRD MSWK RHHL IPET FGVK RRRK RGPV ESDP LRGE PGSA RAAV SELM QLFP RGLF EDAL PPIV LRSQ VYSL VPDR TVAD RQLK ELQE QGEI RIVQ LGFD LDAH GIIF TEDY RTRV LKAC DGRP YAGA VQKF LASV LPAC GDLS FQQD QMTQ TFGF RDSE ITHL VNAG VLTV RDAG SWWL AVPG AGRF IKYF VKGR QAVL SMVR KAKY RELL LSEL LGRR APVV VRLG LTYH VHDL IGAQ LVDC ISTT SGTL LRLP ET
Gene ID:8859
Uniprot:P49842
Cellular Location:Nucleus
Calculated MW:28kDa/40kDa
Observed MW:35kDa
Synonyms:STK19, D6S60, D6S60E, G11, HLA-RP1, RP1
Background:This gene encodes a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 and expresses two transcript variants.
UniProt Protein Function:G11: an atypical protein kinase. Encoded within the major histocompatibility complex. Four alternatively spliced isoforms have been described.
UniProt Protein Details:

Protein type:Kinase, protein; EC 2.7.11.1; Protein kinase, atypical; Protein kinase, Ser/Thr (non-receptor); ATYPICAL group; G11 family

Chromosomal Location of Human Ortholog: 6p21.3

Biological Process: protein amino acid phosphorylation

NCBI Summary:This gene encodes a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 and expresses two transcript variants. [provided by RefSeq, Jul 2008]
UniProt Code:P49842
NCBI GenInfo Identifier:19860281
NCBI Gene ID:8859
NCBI Accession:P49842.2
UniProt Secondary Accession:P49842,Q13159, Q31617, Q5JP77, Q5ST72, Q5ST75, A6NF95 A6NFW8, B0QZR5,
UniProt Related Accession:P49842
Molecular Weight:28,465 Da
NCBI Full Name:Serine/threonine-protein kinase 19
NCBI Synonym Full Names:serine/threonine kinase 19
NCBI Official Symbol:STK19  
NCBI Official Synonym Symbols:G11; RP1; D6S60; D6S60E; HLA-RP1  
NCBI Protein Information:serine/threonine-protein kinase 19
UniProt Protein Name:Serine/threonine-protein kinase 19
UniProt Synonym Protein Names:Protein G11; Protein RP1
Protein Family:Serine/threonine-protein kinase
UniProt Gene Name:STK19  
UniProt Entry Name:STK19_HUMAN
Anti-STK19 Antibody (CAB7574)Western blot analysis of extracts of various cell lines, using STK19 antibody (CAB7574) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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