Cell Biology Antibodies 13
Anti-STEAP1 Antibody (CAB17684)
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- SKU:
- CAB17684
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-STEAP1 Antibody |
| Antibody SKU: | CAB17684 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human STEAP1 (NP_036581.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | PC-3, HepG2, DU145, Mouse testis, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human STEAP1 (NP_036581.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MESR KDIT NQEE LWKM KPRR NLEE DDYL HKDT GETS MLKR PVLL HLHQ TAHA DEFD CPSE LQHT QELF PQWH LPIK IAAI |
| Gene ID: | 26872 |
| Uniprot: | Q9UHE8 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 40kDa |
 | Western blot - STEAP1 Polyclonal Antibody (CAB17684) |
| Synonyms: | PRSS24, STEAP, STEAP1 |
| Background: | This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | STEAP1: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Belongs to the STEAP family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; EC 1.16.1.-; Oxidoreductase; Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 7q21 Cellular Component: endosome; integral to plasma membrane; intercellular junction; membrane; plasma membrane Molecular Function:channel activity; cupric reductase activity; transporter activity Biological Process: copper ion import |
| NCBI Summary: | This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UHE8 |
| NCBI GenInfo Identifier: | 12643440 |
| NCBI Gene ID: | 26872 |
| NCBI Accession: | Q9UHE8.1 |
| UniProt Secondary Accession: | Q9UHE8,O95034, A4D1E0, |
| UniProt Related Accession: | Q9UHE8 |
| Molecular Weight: | 39,851 Da |
| NCBI Full Name: | Metalloreductase STEAP1 |
| NCBI Synonym Full Names: | six transmembrane epithelial antigen of the prostate 1 |
| NCBI Official Symbol: | STEAP1 |
| NCBI Official Synonym Symbols: | STEAP; PRSS24 |
| NCBI Protein Information: | metalloreductase STEAP1 |
| UniProt Protein Name: | Metalloreductase STEAP1 |
| UniProt Synonym Protein Names: | Six-transmembrane epithelial antigen of prostate 1 |
| Protein Family: | Metalloreductase |
| UniProt Gene Name: | STEAP1 |
| UniProt Entry Name: | STEA1_HUMAN |
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