Name: Anti-STARD5 Antibody (CAB13901)
Brand: Cell Biology Antibodies 4
SKU: CAB13901
Availability: OutOfStock

Antibody Name:	Anti-STARD5 Antibody
Antibody SKU:	CAB13901
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human STARD5 (NP_871629.1).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human
Positive Samples:	HT-29, 293T

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human STARD5 (NP_871629.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MDPA LAAQ MSEA VAEK MLQY RRDT AGWK ICRE GNGV SVSW RPSV EFPG NLYR GEGI VYGT LEEV WDCV KPAV GGLR VKWD ENVT GFEI IQSI TDTL CVSR TSTP SAAM KLIS PRDF VDLV LVKR YEDG TISS NATH VEHP LCPP KPGF VRGF NHPC GCFC EPLP GEPT KTNL VTFF HTDL SGYL PQNV VDSF FPRS MTRF YANL QKAV KQFH E
Gene ID:	80765
Uniprot:	Q9NSY2
Cellular Location:
Calculated MW:	7kDa/23kDa
Observed MW:	24kDa

Synonyms:

STARD5

Background:

Proteins containing a steroidogenic acute regulatory-related lipid transfer (START) domain are often involved in the trafficking of lipids and cholesterol between diverse intracellular membranes. This gene is a member of the StarD subfamily that encodes START-related lipid transfer proteins. The protein encoded by this gene is a cholesterol transporter and is also able to bind and transport other sterol-derived molecules related to the cholesterol/bile acid biosynthetic pathways such as 25-hydroxycholesterol. Its expression is upregulated during endoplasmic reticulum (ER) stress. The protein is thought to act as a cytosolic sterol transporter that moves cholesterol between intracellular membranes such as from the cytoplasm to the ER and from the ER to the Golgi apparatus. Alternative splicing of this gene produces multiple transcript variants.

UniProt Protein Function:	STARD5: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Chromosomal Location of Human Ortholog: 15q26 Cellular Component: cytosol Biological Process: C21-steroid hormone biosynthetic process
NCBI Summary:	Proteins containing a steroidogenic acute regulatory-related lipid transfer (START) domain are often involved in the trafficking of lipids and cholesterol between diverse intracellular membranes. This gene is a member of the StarD subfamily that encodes START-related lipid transfer proteins. The protein encoded by this gene is a cholesterol transporter and is also able to bind and transport other sterol-derived molecules related to the cholesterol/bile acid biosynthetic pathways such as 25-hydroxycholesterol. Its expression is upregulated during endoplasmic reticulum (ER) stress. The protein is thought to act as a cytosolic sterol transporter that moves cholesterol between intracellular membranes such as from the cytoplasm to the ER and from the ER to the Golgi apparatus. Alternative splicing of this gene produces multiple transcript variants. [provided by RefSeq, Jan 2016]
UniProt Code:	Q9NSY2
NCBI GenInfo Identifier:	25091329
NCBI Gene ID:	80765
NCBI Accession:	Q9NSY2.2
UniProt Secondary Accession:	Q9NSY2,P59094,
UniProt Related Accession:	Q9NSY2
Molecular Weight:	7,094 Da
NCBI Full Name:	StAR-related lipid transfer protein 5
NCBI Synonym Full Names:	StAR related lipid transfer domain containing 5
NCBI Official Symbol:	STARD5
NCBI Protein Information:	stAR-related lipid transfer protein 5
UniProt Protein Name:	StAR-related lipid transfer protein 5
UniProt Synonym Protein Names:	START domain-containing protein 5; StARD5
Protein Family:	StAR-related lipid transfer protein
UniProt Gene Name:	STARD5
UniProt Entry Name:	STAR5_HUMAN

Western blot analysis of extracts of various cell lines, using STARD5 antibody (CAB13901) at 1:300 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.

Antibodies

STARD5 Antibody (PACO12507)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)