Cell Biology Antibodies 11
Anti-STARD3 Antibody (CAB7776)
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- SKU:
- CAB7776
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-STARD3 Antibody |
| Antibody SKU: | CAB7776 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-445 of human STARD3 (NP_006795.3). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, SKOV3, MCF7, A-549, Mouse lung, Mouse brain, Mouse heart, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-445 of human STARD3 (NP_006795.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DFKV LPQE AEEE RWYL AAQV AVAR GPLL FSGA LSEG QFYS PPES FAGS DNES DEEV AGKK SFSA QERE YIRQ GKEA TAVV DQIL AQEE NWKF EKNN EYGD TVYT IEVP FHGK TFIL KTFL PCPA ELVY QEVI LQPE RMVL WNKT VTAC QILQ RVED NTLI SYDV SAGA AGGV VSPR DFVN VRRI ERRR DRYL SSGI ATSH SAKP PTHK YVRG ENGP GGFI VLKS ASNP RVCT FVWI LNTD LKGR LPRY LIHQ SLAA TMFE FAFH LRQR ISEL GARA |
| Gene ID: | 10948 |
| Uniprot: | Q14849 |
| Cellular Location: | Late endosome membrane, Multi-pass membrane protein |
| Calculated MW: | 48kDa/49kDa/50kDa |
| Observed MW: | 45kDa |
| Synonyms: | STARD3, CAB1, MLN64, es64 |
| Background: | This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | STARD3: Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 17q11-q12 Cellular Component: mitochondrion; late endosome membrane; lysosomal membrane; cytoplasm; integral to membrane Molecular Function:protein binding; cholesterol transporter activity; cholesterol binding Biological Process: steroid metabolic process; cholesterol metabolic process; progesterone biosynthetic process; cholesterol transport; lipid metabolic process; mitochondrial transport |
| NCBI Summary: | This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009] |
| UniProt Code: | Q14849 |
| NCBI GenInfo Identifier: | 116242802 |
| NCBI Gene ID: | 10948 |
| NCBI Accession: | Q14849.2 |
| UniProt Related Accession: | Q14849 |
| Molecular Weight: | Observed: 50 kDaPredicted: 51 kDa |
| NCBI Full Name: | StAR-related lipid transfer protein 3 |
| NCBI Synonym Full Names: | StAR related lipid transfer domain containing 3 |
| NCBI Official Symbol: | STARD3 |
| NCBI Official Synonym Symbols: | CAB1; es64; MLN64 |
| NCBI Protein Information: | stAR-related lipid transfer protein 3 |
| UniProt Protein Name: | StAR-related lipid transfer protein 3 |
| UniProt Synonym Protein Names: | Metastatic lymph node gene 64 protein; MLN 64; Protein CAB1; START domain-containing protein 3; StARD3 |
| Protein Family: | MLN64 N-terminal domain |
| UniProt Gene Name: | STARD3 |
| UniProt Entry Name: | STAR3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using STARD3 antibody (CAB7776) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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