Cell Biology Antibodies 10
Anti-ST8SIA4 Antibody (CAB6754)
(No reviews yet)
Write a Review
- SKU:
- CAB6754
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ST8SIA4 Antibody |
| Antibody SKU: | CAB6754 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-168 of human ST8SIA4 (NP_778222.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | A-549, NCI-H460, HL-60 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-168 of human ST8SIA4 (NP_778222.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | YKTK EIAR TEEH QETQ LIGD GELS LSRS LVNS SDKI IRKA GSSI FQHN VEGW KINS SLVL EIRK NILR FLDA ERDV SVVK SSFK PGDV IHYV LDRR RTLN ISHD LHSL LPEV SPMK NRRF KTCA VVGN SGIL LDSE CGKE IDSH NFVI R |
| Gene ID: | 7903 |
| Uniprot: | Q92187 |
| Cellular Location: | Golgi apparatus membrane, Single-pass type II membrane protein |
| Calculated MW: | 19kDa/41kDa |
| Observed MW: | 41kDa |
| Synonyms: | ST8SIA4, PST, PST1, SIAT8D, ST8SIA-IV |
| Background: | The protein encoded by this gene catalyzes the polycondensation of alpha-2, 8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | ST8SIA4: Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. Belongs to the glycosyltransferase 29 family. |
| UniProt Protein Details: | Protein type:Transferase; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; EC 2.4.99.-; Membrane protein, integral Chromosomal Location of Human Ortholog: 5q21 Cellular Component: Golgi membrane; integral to Golgi membrane Molecular Function:alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; sialic acid binding Biological Process: axon guidance; nervous system development; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; protein modification process; protein amino acid glycosylation; protein amino acid N-linked glycosylation via asparagine; N-glycan processing; post-translational protein modification; oligosaccharide metabolic process; ganglioside biosynthetic process |
| NCBI Summary: | The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92187 |
| NCBI GenInfo Identifier: | 2494834 |
| NCBI Gene ID: | 7903 |
| NCBI Accession: | Q92187.1 |
| UniProt Secondary Accession: | Q92187,Q8N1F4, Q92693, A8KA07, G3V104, |
| UniProt Related Accession: | Q92187 |
| Molecular Weight: | 359 |
| NCBI Full Name: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase |
| NCBI Synonym Full Names: | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| NCBI Official Symbol: | ST8SIA4 |
| NCBI Official Synonym Symbols: | PST; PST1; SIAT8D; ST8SIA-IV |
| NCBI Protein Information: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; SIAT8-D; ST8SiaIV; sialyltransferase 8D; polysialyltransferase-1; sialytransferase St8Sia IV; sialyltransferase St8Sia IV; alpha-2,8-sialyltransferase 8D; sialyltransferase 8 (alpha-2, 8-polysialytransferase) D; CMP-N-acetylneuraminate-poly-alpha-2,8-sialyl transferase |
| UniProt Protein Name: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase |
| UniProt Synonym Protein Names: | Alpha-2,8-sialyltransferase 8D; Polysialyltransferase-1; Sialyltransferase 8D; SIAT8-D; Sialyltransferase St8Sia IV; ST8SiaIV |
| Protein Family: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase |
| UniProt Gene Name: | ST8SIA4 |
| UniProt Entry Name: | SIA8D_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ST8SIA4 Antibody (CAB6754) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s. |
View AllClose
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Anti-MMUT Antibody (CAB9406)
OverviewAntibody Name:Anti-MMUT Antibody (CAB9406)Antibody SKU:CAB9406Antibody Size:50µL, 100µLApplication:Western blotting, Immunohistochemistry