Cell Biology Antibodies 4
Anti-ST7 Antibody (CAB14384)
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- SKU:
- CAB14384
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ST7 Antibody |
| Antibody SKU: | CAB14384 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-290 of human ST7 (NP_068708.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-290 of human ST7 (NP_068708.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QARI SAAH EALE INEI RSRV EVPL IASS TIWE IKLL PKCA TAYI LLAE EEAT TIAE AEKL FKQA LKAG DGCY RRSQ QLQH HGSQ YEAQ HRR |
| Gene ID: | 7982 |
| Uniprot: | Q9NRC1 |
| Cellular Location: | Membrane, Multi-pass membrane protein |
| Calculated MW: | 45kDa/56kDa/58kDa/60kDa/62kDa/63kDa/67kDa |
| Observed MW: | Refer to Figures |
| Synonyms: | ST7, ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7 |
| Background: | The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described. |
| UniProt Protein Function: | ST7: May act as a tumor suppressor. Belongs to the ST7 family. 7 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 7q31.2 Cellular Component: integral to membrane |
| NCBI Summary: | The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NRC1 |
| NCBI GenInfo Identifier: | 74734319 |
| NCBI Gene ID: | 7982 |
| NCBI Accession: | Q9NRC1.1 |
| UniProt Related Accession: | Q9NRC1 |
| Molecular Weight: | 43kDa |
| NCBI Full Name: | Suppressor of tumorigenicity 7 protein |
| NCBI Synonym Full Names: | suppression of tumorigenicity 7 |
| NCBI Official Symbol: | ST7 |
| NCBI Official Synonym Symbols: | HELG; RAY1; SEN4; TSG7; ETS7q; FAM4A; FAM4A1 |
| NCBI Protein Information: | suppressor of tumorigenicity 7 protein |
| UniProt Protein Name: | Suppressor of tumorigenicity 7 protein |
| UniProt Synonym Protein Names: | Protein FAM4A1; Protein HELG |
| Protein Family: | Suppressor of tumorigenicity 7 protein |
| UniProt Gene Name: | ST7 |
| UniProt Entry Name: | ST7_HUMAN |
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