Cell Biology Antibodies 17
Anti-SSTR5 Antibody (CAB8698)
(No reviews yet)
Write a Review
- SKU:
- CAB8698
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SSTR5 Antibody |
| Antibody SKU: | CAB8698 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human SSTR5 |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HT-29, 293T, NIH/3T3, SH-SY5Y, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human SSTR5 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6755 |
| Uniprot: | P35346 |
| Cellular Location: | |
| Calculated MW: | 42kDa |
| Observed MW: | 45KDa |
| Synonyms: | SS-5-R |
| Background: | Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010] |
| UniProt Protein Function: | SSTR5: Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 1; Cell cycle regulation; Receptor, GPCR; Membrane protein, integral Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: neuron projection; integral to plasma membrane; plasma membrane Molecular Function:neuropeptide binding; somatostatin receptor activity Biological Process: positive regulation of cytokinesis; negative regulation of cell proliferation; G-protein signaling, coupled to cyclic nucleotide second messenger; synaptic transmission; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; glucose homeostasis; regulation of insulin secretion Disease: Pituitary Adenoma, Growth Hormone-secreting |
| NCBI Summary: | Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010] |
| UniProt Code: | P35346 |
| NCBI GenInfo Identifier: | 12644225 |
| NCBI Gene ID: | 6755 |
| NCBI Accession: | P35346.3 |
| UniProt Secondary Accession: | P35346,P34988, Q541E0, Q9UJI5, |
| UniProt Related Accession: | P35346,AAB31829 |
| Molecular Weight: | |
| NCBI Full Name: | Somatostatin receptor type 5 |
| NCBI Synonym Full Names: | somatostatin receptor 5 |
| NCBI Official Symbol: | SSTR5 |
| NCBI Official Synonym Symbols: | SS-5-R |
| NCBI Protein Information: | somatostatin receptor type 5; somatostatin receptor subtype 5 |
| UniProt Protein Name: | Somatostatin receptor type 5 |
| UniProt Gene Name: | SSTR5 |
| UniProt Entry Name: | SSR5_HUMAN |
 | Western blot - SSTR5 Rabbit mAb (CAB8698) |
View AllClose
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक