Cell Cycle Antibodies 1
Anti-SSSCA1 Antibody (CAB10137)
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- SKU:
- CAB10137
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
| Antibody Name: | Anti-SSSCA1 Antibody |
| Antibody SKU: | CAB10137 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human SSSCA1 (NP_006387.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human SSSCA1 (NP_006387.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MALN GAEV DDFS WEPP TEAE TKVL QARR ERQD RISR LMGD YLLR GYRM LGET CADC GTIL LQDK QRKI YCVA CQEL DSDV DKDN PALN AQAA LSQA REHQ LASA SELP LGSR PAPQ PPVP RPEH CEGA AAGL KAAQ GPPA PAVP PNTD VMAC TQTA LLQK LTWA SAEL GSST SLET SIQL CGLI RACA EALR SLQQ LQH |
| Gene ID: | 10534 |
| Uniprot: | O60232 |
| Cellular Location: | |
| Calculated MW: | 21kDa |
| Observed MW: | 21kDa |
| Synonyms: | SSSCA1, p27 |
| Background: | This antigen is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren's syndrome. Subcellular localization has not yet been established. |
| UniProt Protein Function: | SSSCA1: Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 11q13.1 Molecular Function:protein binding |
| NCBI Summary: | This antigen is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren's syndrome. Subcellular localization has not yet been established. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60232 |
| NCBI GenInfo Identifier: | 5902701 |
| NCBI Gene ID: | 10534 |
| NCBI Accession: | O60232.1 |
| UniProt Related Accession: | O60232 |
| Molecular Weight: | 21,474 Da |
| NCBI Full Name: | Sjoegren syndrome/scleroderma autoantigen 1 |
| NCBI Synonym Full Names: | Sjogren syndrome/scleroderma autoantigen 1 |
| NCBI Official Symbol: | SSSCA1 |
| NCBI Official Synonym Symbols: | p27 |
| NCBI Protein Information: | Sjoegren syndrome/scleroderma autoantigen 1 |
| UniProt Protein Name: | Sjoegren syndrome/scleroderma autoantigen 1 |
| UniProt Synonym Protein Names: | Autoantigen p27 |
| Protein Family: | Sjoegren syndrome/scleroderma autoantigen |
| UniProt Gene Name: | SSSCA1 |
| UniProt Entry Name: | SSA27_HUMAN |
 | Western blot analysis of extracts of mouse liver, using SSSCA1 antibody (CAB10137) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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