Epigenetics & Nuclear Signaling Antibodies 4
Anti-SSBP1 Antibody (CAB6987)
- SKU:
- CAB6987
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Antibody Name: | Anti-SSBP1 Antibody |
Antibody SKU: | CAB6987 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC IF IP |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-148 of human SSBP1 (NP_001243442.1). |
Application: | WB IHC IF IP |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:50 - 1:200 |
Reactivity: | Human, Mouse |
Positive Samples: | HL-60, MCF7, SW620 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-148 of human SSBP1 (NP_001243442.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MFRR PVLQ VLRQ FVRH ESET TTSL VLER SLNR VHLL GRVG QDPV LRQV EGKN PVTI FSLA TNEM WRSG DSEV YQLG DVSQ KTTW HRIS VFRP GLRD VAYQ YVKK GSRI YLEG KIDY GEYM DKNN VRRQ ATTI IADN IIFL SDQT KEKE |
Gene ID: | 6742 |
Uniprot: | Q04837 |
Cellular Location: | Mitochondrion, Mitochondrion matrix, mitochondrion nucleoid |
Calculated MW: | 17kDa |
Observed MW: | 14kDa |
Synonyms: | SSBP1, Mt-SSB, SOSS-B1, SSBP, mtSSB |
Background: |
UniProt Protein Function: | SSBP1: This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA. |
UniProt Protein Details: | Protein type:RNA-binding; Mitochondrial Chromosomal Location of Human Ortholog: 7q34 Cellular Component: mitochondrion; mitochondrial matrix; nucleus Molecular Function:protein binding; chromatin binding; single-stranded DNA binding Biological Process: positive regulation of helicase activity; mitochondrion organization and biogenesis; organelle organization and biogenesis; DNA replication |
NCBI Summary: | SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010] |
UniProt Code: | Q04837 |
NCBI GenInfo Identifier: | 417811 |
NCBI Gene ID: | 6742 |
NCBI Accession: | Q04837.1 |
UniProt Related Accession: | Q04837 |
Molecular Weight: | 148 |
NCBI Full Name: | Single-stranded DNA-binding protein, mitochondrial |
NCBI Synonym Full Names: | single-stranded DNA binding protein 1, mitochondrial |
NCBI Official Symbol: | SSBP1 |
NCBI Official Synonym Symbols: | SSBP; mtSSB; Mt-SSB; SOSS-B1 |
NCBI Protein Information: | single-stranded DNA-binding protein, mitochondrial; PWP1-interacting protein 17 |
UniProt Protein Name: | Single-stranded DNA-binding protein, mitochondrial |
UniProt Synonym Protein Names: | PWP1-interacting protein 17 |
UniProt Gene Name: | SSBP1 |
UniProt Entry Name: | SSBP_HUMAN |
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