Cell Biology Antibodies 13
Anti-SRPK2 Antibody (CAB17536)
- SKU:
- CAB17536
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SRPK2 Antibody |
| Antibody SKU: | CAB17536 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 420-520 of human SRPK2 (NP_872633.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse heart, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 420-520 of human SRPK2 (NP_872633.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NAES DYTY SSSY EQFN GELP NGRH KIPE SQFP EFST SLFS GSLE PVAC GSVL SEGS PLTE QEES SPSH DRSR TVSA SSTG DLPK AKTR AADL LVNP LDPR N |
| Gene ID: | 6733 |
| Uniprot: | P78362 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 120kDa |
 | Western blot - SRPK2 Polyclonal Antibody (CAB17536) |
| Synonyms: | SFRSK2, SRPK2 |
| Background: |
| UniProt Protein Function: | SRPK2: a CMGC kinase of the SRPK family. Phosphorylates the SR (serine/arginine-rich domain) family of splicing factors. Localizes to the nucleus and the cytoplasm. Thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Highly expressed in brain and to a lesser extent other tissues. A second alternatively spliced transcript variant has been described, but its full length nature has not been determined. |
| UniProt Protein Details: | Protein type:Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Protein kinase, CMGC; Kinase, protein; CMGC group; SRPK family Chromosomal Location of Human Ortholog: 7q22-q31.1 Cellular Component: cytoplasm; nucleolus; nucleoplasm; nucleus Molecular Function:ATP binding; magnesium ion binding; protein binding; protein serine/threonine kinase activity Biological Process: angiogenesis; innate immune response; negative regulation of viral genome replication; nuclear speck organization and biogenesis; positive regulation of cell cycle; positive regulation of cell proliferation; positive regulation of neuron apoptosis; positive regulation of viral genome replication; protein amino acid phosphorylation; regulation of nuclear mRNA splicing, via spliceosome; RNA splicing; spliceosome assembly |
| UniProt Code: | P78362 |
| NCBI GenInfo Identifier: | 300669676 |
| NCBI Gene ID: | 6733 |
| NCBI Accession: | P78362.3 |
| UniProt Secondary Accession: | P78362,O75220, O75221, Q6NUL0, Q6V1X2, Q8IYQ3, A8MVX2 |
| UniProt Related Accession: | P78362 |
| Molecular Weight: | 79,029 Da |
| NCBI Full Name: | SRSF protein kinase 2 |
| NCBI Synonym Full Names: | SRSF protein kinase 2 |
| NCBI Official Symbol: | SRPK2 |
| NCBI Official Synonym Symbols: | SFRSK2 |
| NCBI Protein Information: | SRSF protein kinase 2 |
| UniProt Protein Name: | SRSF protein kinase 2 |
| UniProt Synonym Protein Names: | SFRS protein kinase 2; Serine/arginine-rich protein-specific kinase 2; SR-protein-specific kinase 2 |
| Protein Family: | SRSF protein kinase |
| UniProt Gene Name: | SRPK2 |
| UniProt Entry Name: | SRPK2_HUMAN |
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