Cell Biology Antibodies 9
Anti-SRP9 Antibody (CAB4124)
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- SKU:
- CAB4124
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SRP9 Antibody |
| Antibody SKU: | CAB4124 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-86 of human SRP9 (NP_003124.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:1000 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | A-431 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-86 of human SRP9 (NP_003124.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MPQY QTWE EFSR AAEK LYLA DPMK ARVV LKYR HSDG NLCV KVTD DLVC LVYK TDQA QDVK KIEK FHSQ LMRL MVAK EARN VTME TE |
| Gene ID: | 6726 |
| Uniprot: | P49458 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 9kDa/10kDa |
| Observed MW: | 12kDa |
| Synonyms: | SRP9, ALURBP |
| Background: |
| UniProt Protein Function: | SRP9: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. Belongs to the SRP9 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Translation; RNA-binding Chromosomal Location of Human Ortholog: 1q42.12 Cellular Component: signal recognition particle receptor complex; signal recognition particle, endoplasmic reticulum targeting; cytosol Molecular Function:signal recognition particle binding; RNA binding; 7S RNA binding Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; negative regulation of translational elongation; gene expression |
| UniProt Code: | P49458 |
| NCBI GenInfo Identifier: | 1351111 |
| NCBI Gene ID: | 6726 |
| NCBI Accession: | P49458.2 |
| UniProt Secondary Accession: | P49458,Q6NVX0, Q8WTW0, A8K0N0, |
| UniProt Related Accession: | P49458 |
| Molecular Weight: | 86 |
| NCBI Full Name: | Signal recognition particle 9 kDa protein |
| NCBI Synonym Full Names: | signal recognition particle 9kDa |
| NCBI Official Symbol: | SRP9 |
| NCBI Official Synonym Symbols: | ALURBP |
| NCBI Protein Information: | signal recognition particle 9 kDa protein; signal recognition particle 9kD |
| UniProt Protein Name: | Signal recognition particle 9 kDa protein |
| Protein Family: | Signal recognition particle 9 kDa protein |
| UniProt Gene Name: | SRP9 |
| UniProt Entry Name: | SRP09_HUMAN |
 | Western blot analysis of extracts of A-431 cells, using SRP9 antibody (CAB4124) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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