Description
| Product Name: | SRP54 Rabbit mAb |
| Product Code: | CAB2296 |
| Size: | 20uL, 50uL, 100uL |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human SRP54 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Jurkat |
| Immunogen: | A synthesized peptide derived from human SRP54 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6729 |
| Uniprot: | P61011 |
| Calculated MW: | 54kDa |
| Observed MW: | 54KDa |
| UniProt Protein Function: | SRP54: Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 14q13.2 Cellular Component: cytoplasm; signal recognition particle, endoplasmic reticulum targeting; nucleolus; nuclear speck; nucleus; cytosol Molecular Function:GTPase activity; ribonucleoprotein binding; GDP binding; GTP binding; drug binding; endoplasmic reticulum signal peptide binding; 7S RNA binding Biological Process: response to drug; SRP-dependent cotranslational protein targeting to membrane, translocation; SRP-dependent cotranslational protein targeting to membrane; protein targeting to ER; cellular protein metabolic process; translation; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; gene expression |
| UniProt Code: | P61011 |
| NCBI GenInfo Identifier: | 46577650 |
| NCBI Gene ID: | 6729 |
| NCBI Accession: | P61011.1 |
| UniProt Secondary Accession: | P61011,P14576, |
| UniProt Related Accession: | P61011 |
| Molecular Weight: | 504 |
| NCBI Full Name: | Signal recognition particle 54 kDa protein |
| NCBI Synonym Full Names: | signal recognition particle 54kDa |
| NCBI Official Symbol: | SRP54 |
| NCBI Protein Information: | signal recognition particle 54 kDa protein; signal recognition particle 54kD |
| UniProt Protein Name: | Signal recognition particle 54 kDa protein |
| Protein Family: | Signal recognition particle |
| UniProt Gene Name: | SRP54 |
| UniProt Entry Name: | SRP54_HUMAN |