Cell Biology Antibodies 10
Anti-SRP19 Antibody (CAB6752)
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- SKU:
- CAB6752
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SRP19 Antibody |
| Antibody SKU: | CAB6752 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human SRP19 (NP_003126.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, MCF7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human SRP19 (NP_003126.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MACA AARS PADQ DRFI CIYP AYLN NKKT IAEG RRIP ISKA VENP TATE IQDV CSAV GLNV FLEK NKMY SREW NRDV QYRG RVRV QLKQ EDGS LCLV QFPS RKSV MLYA AEMI PKLK TRTQ KTGG ADQS LQQG EGSK KGKG KKKK |
| Gene ID: | 6728 |
| Uniprot: | P09132 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 8kDa/12kDa/16kDa |
| Observed MW: | 16kDa |
| Synonyms: | SRP19 |
| Background: |
| UniProt Protein Function: | SRP19: Signal-recognition-particle assembly, binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. Belongs to the SRP19 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 5q21-q22 Cellular Component: nucleoplasm; mitochondrion; cytoplasm; signal recognition particle, endoplasmic reticulum targeting; nucleolus; cytosol; nucleus Molecular Function:7S RNA binding Biological Process: response to drug; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; gene expression; cotranslational protein targeting to membrane |
| UniProt Code: | P09132 |
| NCBI GenInfo Identifier: | 115502457 |
| NCBI Gene ID: | 6728 |
| NCBI Accession: | P09132.3 |
| UniProt Secondary Accession: | P09132,Q05D77, Q96FG6, B2R4E9, D6RCQ5, |
| UniProt Related Accession: | P09132 |
| Molecular Weight: | 144 |
| NCBI Full Name: | Signal recognition particle 19 kDa protein |
| NCBI Synonym Full Names: | signal recognition particle 19kDa |
| NCBI Official Symbol: | SRP19 |
| NCBI Protein Information: | signal recognition particle 19 kDa protein; signal recognition particle 19kD |
| UniProt Protein Name: | Signal recognition particle 19 kDa protein |
| Protein Family: | Signal recognition particle 19 kDa protein |
| UniProt Gene Name: | SRP19 |
| UniProt Entry Name: | SRP19_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SRP19 antibody (CAB6752) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat brain using SRP19 antibody (CAB6752) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human vermiform appendix using SRP19 antibody (CAB6752) at dilution of 1:100 (40x lens). |
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