Epigenetics & Nuclear Signaling Antibodies 1

Anti-SREK1 Antibody (CAB13235)

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SKU:
CAB13235

Description

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Antibody Name:Anti-SREK1 Antibody
Antibody SKU:CAB13235
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SREK1 (NP_631907.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:MCF7, HeLa
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SREK1 (NP_631907.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MTSL MPGA GLLP IPTP NPLT TLGV SLSS LGAI PAAA LDPN IATL GEIP QPPL MGNV DPSK IDEI RRTV YVGN LNSQ TTTA DQLL EFFK QVGE VKFV RMAG DETQ PTRF AFVE FADQ NSVP RALA FNGV MFGD RPLK INHS NNAI VKPP EMTP QAAA KELE EVMK RVRE AQSF ISAA IEPE
Gene ID:140890
Uniprot:Q8WXA9
Cellular Location:Nucleus
Calculated MW:59kDa/71kDa
Observed MW:59kDa
Synonyms:SREK1, SFRS12, SRrp508, SRrp86
Background:This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
UniProt Protein Function:Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3.
NCBI Summary:This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
UniProt Code:Q8WXA9
NCBI GenInfo Identifier:116089325
NCBI Gene ID:140890
NCBI Accession:NP_001070667.1
UniProt Secondary Accession:Q8WXA9,Q2M1J0, Q86X37, A4FTW3,
UniProt Related Accession:Q8WXA9
Molecular Weight:17.3 kDa
NCBI Full Name:splicing regulatory glutamine/lysine-rich protein 1 isoform a
NCBI Synonym Full Names:splicing regulatory glutamic acid and lysine rich protein 1
NCBI Official Symbol:SREK1  
NCBI Official Synonym Symbols:SFRS12; SRrp86; SRrp508  
NCBI Protein Information:splicing regulatory glutamine/lysine-rich protein 1
UniProt Protein Name:Splicing regulatory glutamine/lysine-rich protein 1
UniProt Synonym Protein Names:Serine/arginine-rich-splicing regulatory protein 86; SRrp86; Splicing factor, arginine/serine-rich 12; Splicing regulatory protein 508; SRrp508
Protein Family:Splicing regulatory glutamine/lysine-rich protein
UniProt Gene Name:SREK1  
Anti-SREK1 Antibody (CAB13235)Western blot analysis of extracts of various cell lines, using SREK1 antibody (CAB13235) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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Additional Information

Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
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