Cell Biology Antibodies 12

Anti-SQRDL Antibody (CAB9256)

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SKU:
CAB9256
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-SQRDL Antibody
Antibody SKU:CAB9256
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 211-450 of human SQRDL (NP_067022.1).
Application:WB
Recommended Dilution:WB 1:1000 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, LO2, NIH/3T3, Mouse brain, Mouse kidney, Mouse lung, Mouse liver, Rat intestine
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 211-450 of human SQRDL (NP_067022.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LSEA YFRK TGKR SKAN IIFN TSLG AIFG VKKY ADAL QEII QERN LTVN YKKN LIEV RADK QEAV FENL DKPG ETQV ISYE MLHV TPPM SPPD VLKT SPVA DAAG WVDV DKET LQHR RYPN VFGI GDCT NLPT SKTA AAVA AQSG ILDR TISV IMKN QTPT KKYD GYTS CPLV TGYN RVIL AEFD YKAE PLET FPFD QSKE RLSM YLMK ADLM PFLY WNMM LRGY WGGP AFLR KLFH LGMS
Gene ID:58472
Uniprot:Q9Y6N5
Cellular Location:Mitochondrion
Calculated MW:49kDa
Observed MW:48kDa
Synonyms:SQOR, CGI-44, PRO1975, SQR, SQRDL
Background:The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein.
UniProt Protein Function:SQRDL: Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. Belongs to the SQRD family.
UniProt Protein Details:

Protein type:EC 1.-.-.-; Oxidoreductase; Mitochondrial

Chromosomal Location of Human Ortholog: 15q15

Cellular Component: mitochondrial inner membrane

NCBI Summary:The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2012]
UniProt Code:Q9Y6N5
NCBI GenInfo Identifier:27151704
NCBI Gene ID:58472
NCBI Accession:Q9Y6N5.1
UniProt Secondary Accession:Q9Y6N5,Q9UQM8,
UniProt Related Accession:Q9Y6N5
Molecular Weight:49,961 Da
NCBI Full Name:Sulfide:quinone oxidoreductase, mitochondrial
NCBI Synonym Full Names:sulfide quinone reductase-like (yeast)
NCBI Official Symbol:SQRDL  
NCBI Official Synonym Symbols:SQOR; CGI-44; PRO1975  
NCBI Protein Information:sulfide:quinone oxidoreductase, mitochondrial
UniProt Protein Name:Sulfide:quinone oxidoreductase, mitochondrial
Protein Family:Sulfide:quinone oxidoreductase
UniProt Gene Name:SQRDL  
UniProt Entry Name:SQRD_HUMAN
Anti-SQRDL Polyclonal Antibody (CAB9256)Western blot analysis of extracts of various cell lines, using SQRDL antibody (CAB9256) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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