Signal Transduction Antibodies 1

Anti-SPSB1 Antibody (CAB13886)

(No reviews yet) Write a Review
SKU:
CAB13886
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SPSB1 Antibody
Antibody SKU:CAB13886
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human SPSB1 (NP_079382.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, A-549, A375, Mouse spleen, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human SPSB1 (NP_079382.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGQK VTGG IKTV DMRD PTYR PLKQ ELQG LDYC KPTR LDLL LDMP PVSY DVQL LHSW NNND
Gene ID:80176
Uniprot:Q96BD6
Cellular Location:Cytoplasm
Calculated MW:30kDa
Observed MW:31kDa
Synonyms:SPSB1, SSB-1, SSB1
Background:
UniProt Protein Function:SSB1: Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the SPSB family.
UniProt Protein Details:

Protein type:Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: cytosol

Molecular Function:protein binding; ubiquitin-protein ligase activity

Biological Process: protein polyubiquitination

UniProt Code:Q96BD6
NCBI GenInfo Identifier:74731225
NCBI Gene ID:80176
NCBI Accession:Q96BD6.1
UniProt Secondary Accession:Q96BD6,Q59FA1, Q5TIH9, Q9BRY9, Q9H6C5, A2A275,
UniProt Related Accession:Q96BD6
Molecular Weight:Calculated MW: 30 kDaObserved MW: 31 kDa
NCBI Full Name:SPRY domain-containing SOCS box protein 1
NCBI Synonym Full Names:splA/ryanodine receptor domain and SOCS box containing 1
NCBI Official Symbol:SPSB1  
NCBI Official Synonym Symbols:SSB1; SSB-1  
NCBI Protein Information:SPRY domain-containing SOCS box protein 1
UniProt Protein Name:SPRY domain-containing SOCS box protein 1
Protein Family:SPRY domain-containing SOCS box protein
UniProt Gene Name:SPSB1  
Anti-SPSB1 Antibody (CAB13886)Western blot analysis of extracts of various cell lines, using SPSB1 antibody (CAB13886) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
View AllClose

0 Reviews

View AllClose

Related Products