Cell Biology Antibodies 14
Anti-SPON2 Antibody (CAB11990)
- SKU:
- CAB11990
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-SPON2 Antibody |
Antibody SKU: | CAB11990 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-150 of human SPON2 (NP_036577.1). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Mouse, Rat |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-150 of human SPON2 (NP_036577.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | QPLG GESI CSAR APAK YSIT FTGK WSQT AFPK QYPL FRPP AQWS SLLG AAHS SDYS MWRK NQYV SNGL RDFA ERGE AWAL MKEI EAAG EALQ SVHA VFSA PAVP SGTG QTSA ELEV QRRH SLVS |
Gene ID: | 10417 |
Uniprot: | Q9BUD6 |
Cellular Location: | Secreted, extracellular matrix, extracellular space |
Calculated MW: | 35kDa |
Observed MW: | Refer to figures |
Synonyms: | SPON2, DIL-1, DIL1, M-SPONDIN, MINDIN, spondin-2 |
Background: |
UniProt Protein Function: | SPON2: Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern- recognition molecule in the ECM for microbial pathogens. Binds bacterial lipopolysaccharide (LPS). |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 4p16.3 Molecular Function:protein binding Biological Process: axon guidance |
UniProt Code: | Q9BUD6 |
NCBI GenInfo Identifier: | 313104285 |
NCBI Gene ID: | 10417 |
NCBI Accession: | Q9BUD6.3 |
UniProt Secondary Accession: | Q9BUD6,Q4W5N4, Q9ULW1, D3DVN9, |
UniProt Related Accession: | Q9BUD6 |
Molecular Weight: | 36kDa |
NCBI Full Name: | Spondin-2 |
NCBI Synonym Full Names: | spondin 2 |
NCBI Official Symbol: | SPON2 |
NCBI Official Synonym Symbols: | DIL1; DIL-1; MINDIN; M-SPONDIN |
NCBI Protein Information: | spondin-2 |
UniProt Protein Name: | Spondin-2 |
UniProt Synonym Protein Names: | Differentially expressed in cancerous and non-cancerous lung cells 1; DIL-1; Mindin |
Protein Family: | Spondin |
UniProt Gene Name: | SPON2 |