Name: Anti-Spermine synthase Antibody (CAB9154)
Brand: Metabolism Antibodies 3
SKU: CAB9154
Availability: OutOfStock

Antibody Name:	Anti-Spermine synthase Antibody
Antibody SKU:	CAB9154
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-366 of human SMS (NP_004586.2).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse
Positive Samples:	HT-29, 293T, A375, Raji, Mouse brain, Mouse heart, Mouse kidney

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-366 of human SMS (NP_004586.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MAAA RHST LDFM LGAK ADGE TILK GLQS IFQE QGMA ESVH TWQD HGYL ATYT NKNG SFAN LRIY PHGL VLLD LQSY DGDA QGKE EIDS ILNK VEER MKEL SQDS TGRV KRLP PIVR GGAI DRYW PTAD GRLV EYDI DEVV YDED SPYQ NIKI LHSK QFGN ILIL SGDV NLAE SDLA YTRA IMGS GKED YTGK DVLI LGGG DGGI LCEI VKLK PKMV TMVE IDQM VIDG CKKY MRKT CGDV LDNL KGDC YQVL IEDC IPVL KRYA KEGR EFDY VIND LTAV PIST SPEE DSTW EFLR LILD LSMK VLKQ DGKY FTQG NCVN LTEA LSLY EEQL GRLY CPVE FSKE IVCV PSYL ELWV FYTV WKKA KP
Gene ID:	6611
Uniprot:	P52788
Cellular Location:
Calculated MW:	35kDa/41kDa
Observed MW:	41kDa

Synonyms:	SMS, MRSR, SPMSY, SRS, SpS
Background:	This gene encodes a protein belonging to the spermidine/spermin synthase family. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene are associated with X-linked Snyder-Robinson mental retardation syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt Protein Function:	SMS: an ubiquitous enzyme of polyamine metabolism. Synthesizes spermine from spermidine.
UniProt Protein Details:	Protein type:Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - arginine and proline; EC 2.5.1.22; Transferase; Other Amino Acids Metabolism - beta-alanine; Other Amino Acids Metabolism - glutathione Chromosomal Location of Human Ortholog: Xp22.1 Cellular Component: cytosol Molecular Function:spermidine synthase activity; spermine synthase activity Biological Process: methionine metabolic process; spermine biosynthetic process; polyamine metabolic process Disease: Mental Retardation, X-linked, Syndromic, Snyder-robinson Type
NCBI Summary:	This gene encodes a protein belonging to the spermidine/spermin synthase family. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene are associated with X-linked Snyder-Robinson mental retardation syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
UniProt Code:	P52788
NCBI GenInfo Identifier:	21264341
NCBI Gene ID:	6611
NCBI Accession:	NP_004586
UniProt Secondary Accession:	P52788,O00544, Q9UQS1, A6NHA7, A6NI34, B2R9M0,
UniProt Related Accession:	P52788
Molecular Weight:	35,278 Da
NCBI Full Name:	spermine synthase isoform 1
NCBI Synonym Full Names:	spermine synthase
NCBI Official Symbol:	SMS
NCBI Official Synonym Symbols:	SRS; SpS; MRSR; SPMSY
NCBI Protein Information:	spermine synthase
UniProt Protein Name:	Spermine synthase
UniProt Synonym Protein Names:	Spermidine aminopropyltransferase
UniProt Gene Name:	SMS
UniProt Entry Name:	SPSY_HUMAN

Anti-Spermine synthase Polyclonal Antibody (CAB9154)

Western blot analysis of extracts of various cell lines, using SMS antibody (CAB9154) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.

Antibodies

SMS Antibody (PACO12348)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)