Cell Biology Antibodies 14
Anti-SOX11 Antibody (CAB17945)
- SKU:
- CAB17945
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SOX11 Antibody |
| Antibody SKU: | CAB17945 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human SOX11. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxPC-3, SH-SY5Y, HeLa, Mouse brain, mouse heart, rat brain, rat kidney |
| Immunogen: | A synthetic peptide of human SOX11. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6664 |
| Uniprot: | P35716 |
| Cellular Location: | Nucleus |
| Calculated MW: | 46kDa |
| Observed MW: | 60kDa |
 | Western blot - SOX11 Polyclonal Antibody (CAB17945) |
| Synonyms: | SOX11, MRD27 |
| Background: | This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. |
| UniProt Protein Function: | SOX11: Probably important in the developing nervous system. May also have a role in tissue modeling during development. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 2p25.2 Cellular Component: cytoplasm; nucleus Molecular Function:transcription factor activity; translation factor activity, nucleic acid binding Biological Process: embryonic digestive tract morphogenesis; embryonic skeletal morphogenesis; glial cell development; glial cell proliferation; hard palate development; lens morphogenesis in camera-type eye; limb bud formation; negative regulation of lymphocyte proliferation; negative regulation of transcription from RNA polymerase II promoter; neural crest cell development; neural tube formation; neuron differentiation; positive regulation of BMP signaling pathway; positive regulation of cell proliferation; positive regulation of hormone secretion; positive regulation of neurogenesis; positive regulation of neuron differentiation; positive regulation of ossification; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transforming growth factor beta receptor signaling pathway; skeletal development; soft palate development; spinal cord development; sympathetic nervous system development Disease: Mental Retardation, Autosomal Dominant 27 |
| NCBI Summary: | This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P35716 |
| NCBI GenInfo Identifier: | 1351142 |
| NCBI Gene ID: | 6664 |
| NCBI Accession: | P35716.2 |
| UniProt Secondary Accession: | P35716,Q4ZFV8, |
| UniProt Related Accession: | P35716 |
| Molecular Weight: | 46,679 Da |
| NCBI Full Name: | Transcription factor SOX-11 |
| NCBI Synonym Full Names: | SRY-box 11 |
| NCBI Official Symbol: | SOX11 |
| NCBI Official Synonym Symbols: | MRD27 |
| NCBI Protein Information: | transcription factor SOX-11 |
| UniProt Protein Name: | Transcription factor SOX-11 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | SOX11 |
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