Epigenetics & Nuclear Signaling Antibodies 3
Anti-SOX1 Antibody (CAB3086)
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- SKU:
- CAB3086
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-SOX1 Antibody |
| Antibody SKU: | CAB3086 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human SOX1 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T |
| Immunogen: | A synthetic peptide of human SOX1 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6656 |
| Uniprot: | O00570 |
| Cellular Location: | Nucleus |
| Calculated MW: | 39kDa |
| Observed MW: | 50kDa |
| Synonyms: | SOX1, SRY-box 1 |
| Background: | This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. |
| UniProt Protein Function: | SOX1: Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Mainly expressed in the developing central nervous system. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 13q34 Molecular Function:protein binding |
| NCBI Summary: | This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O00570 |
| NCBI GenInfo Identifier: | 206729896 |
| NCBI Gene ID: | 6656 |
| NCBI Accession: | O00570.2 |
| UniProt Secondary Accession: | O00570,Q5W0Q1, |
| UniProt Related Accession: | O00570 |
| Molecular Weight: | 39,023 Da |
| NCBI Full Name: | Transcription factor SOX-1 |
| NCBI Synonym Full Names: | SRY-box 1 |
| NCBI Official Symbol: | SOX1 |
| NCBI Protein Information: | transcription factor SOX-1 |
| UniProt Protein Name: | Transcription factor SOX-1 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | SOX1 |
| UniProt Entry Name: | SOX1_HUMAN |
 | Western blot analysis of extracts of 293T cells, using SOX1 antibody (CAB3086). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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