Anti-Somatostatin (SST) Antibody (CAB20617)
- SKU:
- CAB20617
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SST
- Synonyms:
- SMST
- Research Area:
- Cell Biology
Description
| Product Name: | Somatostatin (SST) Rabbit mAb |
| Product Code: | CAB20617 |
| Size: | 50uL, 100uL |
| Synonyms: | SST, SMST |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-116 of human Somatostatin (SST) (NP_001039.1). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-116 of human Somatostatin (SST) (NP_001039.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6750 |
| Uniprot: | P61278 |
| Cellular Location: | Secreted |
| Calculated MW: | 12kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | SST: Somatostatin inhibits the release of somatotropin. Belongs to the somatostatin family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Hormone Chromosomal Location of Human Ortholog: 3q28 Cellular Component: extracellular space; cell soma; extracellular region Molecular Function:hormone activity Biological Process: response to drug; induction of apoptosis by hormones; response to amino acid stimulus; regulation of cell migration; G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; synaptic transmission; hyperosmotic response; cell surface receptor linked signal transduction; cell-cell signaling; response to heat; response to steroid hormone stimulus; digestion; response to nutrient |
| NCBI Summary: | The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P61278 |
| NCBI GenInfo Identifier: | 4507243 |
| NCBI Gene ID: | 6750 |
| NCBI Accession: | NP_001039.1 |
| UniProt Related Accession: | P61278 |
| Molecular Weight: | |
| NCBI Full Name: | somatostatin preproprotein |
| NCBI Synonym Full Names: | somatostatin |
| NCBI Official Symbol: | SST |
| NCBI Official Synonym Symbols: | SMST |
| NCBI Protein Information: | somatostatin |
| UniProt Protein Name: | Somatostatin |
| UniProt Synonym Protein Names: | Growth hormone release-inhibiting factorCleaved into the following 2 chains:Somatostatin-28; Somatostatin-14 |
| Protein Family: | Sucrose synthase |
| UniProt Gene Name: | SST |
| UniProt Entry Name: | SMS_HUMAN |
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