Cell Biology Antibodies 7
Anti-SOGA1 Antibody (CAB16597)
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- SKU:
- CAB16597
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-SOGA1 Antibody |
| Antibody SKU: | CAB16597 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 650-750 of human SOGA1 (NP_542194.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse liver, Mouse brain, Mouse lung, Rat liver, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 650-750 of human SOGA1 (NP_542194.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AEVL PGLR EQAA LVSK AIDV LVAD ANGF TAGL RLCL DNEC ADFR LHEA PDNS EGPR DTKL IHAI LVRL SVLQ QELN AFTR KADA VLGC SVKE QQES FSSL P |
| Gene ID: | 140710 |
| Uniprot: | O94964 |
| Cellular Location: | Secreted |
| Calculated MW: | 55kDa/115kDa/159kDa/183kDa |
| Observed MW: | 80kDa |
| Synonyms: | SOGA1, C20orf117, KIAA0889, SOGA |
| Background: |
| UniProt Protein Function: | SOGA1: Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner. Belongs to the SOGA family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Autophagy Chromosomal Location of Human Ortholog: 20q11.23 Cellular Component: extracellular space Biological Process: negative regulation of gluconeogenesis; insulin receptor signaling pathway; regulation of autophagy |
| UniProt Code: | O94964 |
| NCBI GenInfo Identifier: | 66773344 |
| NCBI Gene ID: | 140710 |
| NCBI Accession: | NP_954650 |
| UniProt Secondary Accession: | O94964,Q14DB2, Q5JW51, Q6ZTG8, A6NK10, |
| UniProt Related Accession: | O94964 |
| Molecular Weight: | Predicted: 183 kDaObserved: 200kDa |
| NCBI Full Name: | protein SOGA1 isoform 2 |
| NCBI Synonym Full Names: | suppressor of glucose, autophagy associated 1 |
| NCBI Official Symbol: | SOGA1 |
| NCBI Official Synonym Symbols: | SOGA; KIAA0889; C20orf117 |
| NCBI Protein Information: | protein SOGA1; SOGA family member 1; suppressor of glucose by autophagy; suppressor of glucose from autophagy; suppressor of glucose, autophagy-associated protein 1 |
| UniProt Protein Name: | Protein SOGA1 |
| UniProt Synonym Protein Names: | SOGA family member 1; Suppressor of glucose by autophagy; Suppressor of glucose, autophagy-associated protein 1Cleaved into the following 2 chains:N-terminal form; C-terminal 80 kDa form; 80-kDa SOGA fragment |
| Protein Family: | Protein |
| UniProt Gene Name: | SOGA1 |
| UniProt Entry Name: | SOGA1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SOGA1 antibody (CAB16597) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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