Epigenetics & Nuclear Signaling Antibodies 1

Anti-SNRPD2 Antibody (CAB13356)

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SKU:
CAB13356
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-SNRPD2 Antibody
Antibody SKU:CAB13356
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human SNRPD2 (NP_004588.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:MCF7, HL-60, HepG2, HeLa, Jurkat, Mouse testis, Mouse heart, Mouse skeletal muscle, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human SNRPD2 (NP_004588.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSLL NKPK SEMT PEEL QKRE EEEF NTGP LSVL TQSV KNNT QVLI NCRN NKKL LGRV KAFD RHCN MVLE NVKE MWTE VPKS GKGK KKSK PVNK DRYI SKMF LRGD SVIV VLRN PLIA GK
Gene ID:6633
Uniprot:P62316
Cellular Location:Cytoplasm, Nucleus, cytosol
Calculated MW:12kDa/13kDa
Observed MW:14kDa
Synonyms:SNRPD2, SMD2, SNRPD1, Sm-D2
Background:The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:snRNP D2: Required for pre-mRNA splicing. Required for snRNP biogenesis. Belongs to the snRNP core protein family.
UniProt Protein Details:

Protein type:RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: small nuclear ribonucleoprotein complex; nucleoplasm; spliceosome; snRNP U1; cytosol; U12-dependent spliceosome

Molecular Function:protein binding

Biological Process: nuclear mRNA splicing, via spliceosome; spliceosomal snRNP biogenesis; RNA splicing; spliceosome assembly; gene expression

NCBI Summary:The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
UniProt Code:P62316
NCBI GenInfo Identifier:51338666
NCBI Gene ID:6633
NCBI Accession:P62316.1
UniProt Related Accession:P62316
Molecular Weight:
NCBI Full Name:Small nuclear ribonucleoprotein Sm D2
NCBI Synonym Full Names:small nuclear ribonucleoprotein D2 polypeptide
NCBI Official Symbol:SNRPD2  
NCBI Official Synonym Symbols:SMD2; Sm-D2; SNRPD1  
NCBI Protein Information:small nuclear ribonucleoprotein Sm D2
UniProt Protein Name:Small nuclear ribonucleoprotein Sm D2
UniProt Synonym Protein Names:snRNP core protein D2
Protein Family:Probable small nuclear ribonucleoprotein
UniProt Gene Name:SNRPD2  
UniProt Entry Name:SMD2_HUMAN
Anti-SNRPD2 Antibody (CAB13356)Western blot analysis of extracts of various cell lines, using SNRPD2 antibody (CAB13356) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-SNRPD2 Antibody (CAB13356)Immunofluorescence analysis of MCF-7 cells using SNRPD2 antibody (CAB13356). Blue: DAPI for nuclear staining.
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