Epigenetics & Nuclear Signaling Antibodies 3

Anti-SNRPD1 Antibody (CAB14493)

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SKU:
CAB14493
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-SNRPD1 Antibody
Antibody SKU:CAB14493
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SNRPD1 (NP_008869.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse kidney
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SNRPD1 (NP_008869.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MKLV RFLM KLSH ETVT IELK NGTQ VHGT ITGV DVSM NTHL KAVK MTLK NREP VQLE TLSI RGNN IRYF ILPD SLPL DTLL VDVE PKVK SKKR EAVA GRGR
Gene ID:6632
Uniprot:P62314
Cellular Location:Cytoplasm, Nucleus, cytosol
Calculated MW:13kDa
Observed MW:16kDa
Synonyms:SNRPD1, HsT2456, SMD1, SNRPD, Sm-D1
Background:This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. Two transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:snRNP D1: May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA. Belongs to the snRNP core protein family.
UniProt Protein Details:

Protein type:RNA splicing; Spliceosome; RNA-binding

Chromosomal Location of Human Ortholog: 18q11.2

Cellular Component: nucleoplasm; small nuclear ribonucleoprotein complex; snRNP U1; cytosol; nucleus; U12-dependent spliceosome

Molecular Function:protein binding; RNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; spliceosomal snRNP biogenesis; RNA splicing; spliceosome assembly; gene expression

NCBI Summary:This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
UniProt Code:P62314
NCBI GenInfo Identifier:51338665
NCBI Gene ID:6632
NCBI Accession:P62314.1
UniProt Secondary Accession:P62314,P13641, B5BTZ1,
UniProt Related Accession:P62314
Molecular Weight:119
NCBI Full Name:Small nuclear ribonucleoprotein Sm D1
NCBI Synonym Full Names:small nuclear ribonucleoprotein D1 polypeptide 16kDa
NCBI Official Symbol:SNRPD1  
NCBI Official Synonym Symbols:SMD1; SNRPD; Sm-D1; HsT2456  
NCBI Protein Information:small nuclear ribonucleoprotein Sm D1; Sm-D autoantigen; snRNP core protein D1; small nuclear ribonucleoprotein D1 polypeptide 16kDa pseudogene
UniProt Protein Name:Small nuclear ribonucleoprotein Sm D1
UniProt Synonym Protein Names:Sm-D autoantigen; snRNP core protein D1
Protein Family:Small nuclear ribonucleoprotein
UniProt Gene Name:SNRPD1  
UniProt Entry Name:SMD1_HUMAN
Anti-SNRPD1 Antibody (CAB14493)Western blot analysis of extracts of mouse kidney, using SNRPD1 antibody (CAB14493) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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