Epigenetics & Nuclear Signaling Antibodies 2

Anti-SNRNP200 Antibody (CAB6063)

(No reviews yet) Write a Review
SKU:
CAB6063
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SNRNP200 Antibody
Antibody SKU:CAB6063
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200 (NP_054733.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:Jurkat, A-431, HepG2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200 (NP_054733.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QMVT QAMW SKDS YLKQ LPHF TSEH IKRC TDKG VESV FDIM EMED EERN ALLQ LTDS QIAD VARF CNRY PNIE LSYE VVDK DSIR SGGP VVVL VQLE REEE VTGP VIAP LFPQ KREE GWWV VIGD AKSN SLIS IKRL TLQQ KAKV KLDF VAPA TGAH NYTL YFMS DAYM GCDQ EYKF SVDV KEAE TDSD SD
Gene ID:23020
Uniprot:O75643
Cellular Location:Nucleus
Calculated MW:71kDa/244kDa
Observed MW:244kDa
Synonyms:SNRNP200, ASCC3L1, BRR2, HELIC2, RP33, U5-200KD, SNRNP200
Background:Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
UniProt Code:O75643
NCBI GenInfo Identifier:56405304
NCBI Gene ID:23020
NCBI Accession:O75643.2
UniProt Secondary Accession:O75643,O94884, Q6NZY0, Q6PX59, Q8NBE6, Q96IF2, Q9H7S0
UniProt Related Accession:O75643
Molecular Weight:2136
NCBI Full Name:U5 small nuclear ribonucleoprotein 200 kDa helicase
NCBI Synonym Full Names:small nuclear ribonucleoprotein 200kDa (U5)
NCBI Official Symbol:SNRNP200  
NCBI Official Synonym Symbols:BRR2; RP33; HELIC2; ASCC3L1; U5-200KD  
NCBI Protein Information:U5 small nuclear ribonucleoprotein 200 kDa helicase; BRR2 homolog; U5 snRNP-specific 200 kDa protein; activating signal cointegrator 1 complex subunit 3-like 1
UniProt Protein Name:U5 small nuclear ribonucleoprotein 200 kDa helicase
UniProt Synonym Protein Names:Activating signal cointegrator 1 complex subunit 3-like 1; BRR2 homolog; U5 snRNP-specific 200 kDa protein; U5-200KD
Protein Family:U5 small nuclear ribonucleoprotein 200 kDa helicase
UniProt Gene Name:SNRNP200  
UniProt Entry Name:U520_HUMAN
Anti-SNRNP200 Antibody (CAB6063)Western blot analysis of extracts of various cell lines, using SNRNP200 antibody (CAB6063) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products