Epigenetics & Nuclear Signaling Antibodies 2
Anti-SNAPC1 Antibody (CAB15725)
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- SKU:
- CAB15725
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-SNAPC1 Antibody |
| Antibody SKU: | CAB15725 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human SNAPC1 (NP_003073.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-431, U-87MG, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human SNAPC1 (NP_003073.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGTP PGLQ TDCE ALLS RFQE TDSV RFED FTEL WRNM KFGT IFCG RMRN LEKN MFTK EALA LAWR YFLP PYTF QIRV GALY LLYG LYNT QLCQ PKQK IRVA LKDW DEVL KFQQ DLVN AQHF DAAY IFRK LRLD RAFH FTAM PKLL SYRM KKKI HRAE VTEE FKDP SDRV MKLI TSDV LEEM LNVH DHYQ NMKH VISV DKSK PDKA LSLI KDDF FDNI KNIV LEHQ QWHK DRKN PSLK SKTN DGEE KMEG NSQE TERC ERAE SLAK IKSK AFSV VIQA SKSR RHRQ VKLD SSDS DSAS GQGQ VKAT RKKE KKER LKPA GRKM SLRN KGNV QNIH KEDK PLSL SMPV ITEE EENE SLSG TEFT ASKK RRKH |
| Gene ID: | 6617 |
| Uniprot: | Q16533 |
| Cellular Location: | Nucleus |
| Calculated MW: | 42kDa |
| Observed MW: | 50-55kDa |
| Synonyms: | SNAPC1, PTFgamma, SNAP43 |
| Background: |
| UniProt Protein Function: | SNAPC1: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 14q22 Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus; snRNA-activating protein complex Molecular Function:sequence-specific DNA binding Biological Process: snRNA transcription from RNA polymerase II promoter; snRNA transcription from RNA polymerase III promoter |
| UniProt Code: | Q16533 |
| NCBI GenInfo Identifier: | 8134716 |
| NCBI Gene ID: | 6617 |
| NCBI Accession: | Q16533.1 |
| UniProt Related Accession: | Q16533 |
| Molecular Weight: | 42,994 Da |
| NCBI Full Name: | snRNA-activating protein complex subunit 1 |
| NCBI Synonym Full Names: | small nuclear RNA activating complex polypeptide 1 |
| NCBI Official Symbol: | SNAPC1 |
| NCBI Official Synonym Symbols: | SNAP43; PTFgamma |
| NCBI Protein Information: | snRNA-activating protein complex subunit 1 |
| UniProt Protein Name: | snRNA-activating protein complex subunit 1 |
| UniProt Synonym Protein Names: | Proximal sequence element-binding transcription factor subunit gamma; PSE-binding factor subunit gamma; PTF subunit gamma; Small nuclear RNA-activating complex polypeptide 1; snRNA-activating protein complex 43 kDa subunit; SNAPc 43 kDa subunit |
| Protein Family: | snRNA-activating protein complex |
| UniProt Gene Name: | SNAPC1 |
| UniProt Entry Name: | SNPC1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SNAPC1 antibody (CAB15725) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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