Cell Biology Antibodies 10

Anti-SNAP91 Antibody (CAB6746)

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SKU:
CAB6746
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-SNAP91 Antibody
Antibody SKU:CAB6746
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human SNAP91 (NP_001229723.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Rat brain, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 321-600 of human SNAP91 (NP_001229723.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AVPV STSK PSSD LLDL QPDF SSGG AAAA AAPA PPPP AGGA TAWG GFGG SFMA PSPS PVTP AQNN LLQP NFEA AFGT TPST SSSS SFDP SVFD GLGD LLMP TMAP AGQP APVS MVPP SPAM AASK ALGS DLDS SLAS LVGN LGIS GTTT KKGD LQWN AGEK KLTG GANW QPKV APAT WSAG VPPS APLQ GAVP PTSS VPPV AGAP SVGQ PGAG FGMP PAGT GMPM MPQQ PVMF AQPM MRPP FGAA AVPG TQLS PSPT PASQ SPKK PPAK DPLA DLNI KDFL
Gene ID:9892
Uniprot:O60641
Cellular Location:Cell membrane, Cytoplasmic side, Membrane, Peripheral membrane protein, coated pit
Calculated MW:6kDa/63kDa/89kDa/92kDa
Observed MW:180kDa
Synonyms:SNAP91, AP180, CALM
Background:
UniProt Protein Function:SNAP-91: Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia induces their assembly into 60-70 nm coats. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Vesicle

Chromosomal Location of Human Ortholog: 6q14.2

Cellular Component: clathrin-coated vesicle; plasma membrane; coated pit

Molecular Function:clathrin binding; protein binding; protein kinase binding; phosphatidylinositol binding

Biological Process: clathrin cage assembly; synaptic transmission; protein transport

UniProt Code:O60641
NCBI GenInfo Identifier:27805394
NCBI Gene ID:9892
NCBI Accession:O60641.2
UniProt Secondary Accession:O60641,Q5JX13, Q68DL9, Q6P9D3, Q9NTY7, A8K0L7, E5RI02
UniProt Related Accession:O60641
Molecular Weight:907
NCBI Full Name:Clathrin coat assembly protein AP180
NCBI Synonym Full Names:synaptosomal-associated protein, 91kDa
NCBI Official Symbol:SNAP91  
NCBI Official Synonym Symbols:CALM; AP180  
NCBI Protein Information:clathrin coat assembly protein AP180; phosphoprotein F1-20; assembly protein, 180kDa; 91 kDa synaptosomal-associated protein; clathrin coat-associated protein AP180; synaptosomal-associated protein, 91kDa homolog
UniProt Protein Name:Clathrin coat assembly protein AP180
UniProt Synonym Protein Names:91 kDa synaptosomal-associated protein; Clathrin coat-associated protein AP180; Phosphoprotein F1-20
Protein Family:Clathrin coat assembly protein
UniProt Gene Name:SNAP91  
UniProt Entry Name:AP180_HUMAN
Anti-SNAP91 Antibody (CAB6746)Western blot analysis of extracts of various cell lines, using SNAP91 antibody (CAB6746) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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