Anti-SMYD3 Antibody (CAB2262)
- SKU:
- CAB2262
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- KMT3E
- Synonyms:
- ZMYND1
- Synonyms:
- ZNFN3A1
- Synonyms:
- bA74P14.1
- Research Area:
- Cell Biology
Description
| Product Name: | SMYD3 Rabbit mAb |
| Product Code: | CAB2262 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | KMT3E, ZMYND1, ZNFN3A1, bA74P14.1 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human SMYD3 |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HCT116, MCF7, Mouse thymus, Rat brain |
| Immunogen: | A synthesized peptide derived from human SMYD3 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 64754 |
| Uniprot: | Q9H7B4 |
| Calculated MW: | 42kDa |
| Observed MW: | 42kDa |
| UniProt Protein Function: | SMYD3: Histone methyltransferase. Specifically methylates 'Lys- 4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. Belongs to the histone-lysine methyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.1.1.43; Methyltransferase, protein lysine; Methyltransferase Chromosomal Location of Human Ortholog: 1q44 Cellular Component: nucleoplasm; cytoplasm Molecular Function:metal ion binding; histone-lysine N-methyltransferase activity Biological Process: nucleosome assembly; establishment and/or maintenance of chromatin architecture; establishment of protein localization; myotube cell development; negative regulation of protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation |
| NCBI Summary: | This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| UniProt Code: | Q9H7B4 |
| NCBI GenInfo Identifier: | 212276523 |
| NCBI Gene ID: | 64754 |
| NCBI Accession: | Q9H7B4.4 |
| UniProt Secondary Accession: | Q9H7B4,Q86TL8, Q8N5Z6, Q96AI5, A8K0P0, B1AN38, |
| UniProt Related Accession: | Q9H7B4 |
| Molecular Weight: | 428 |
| NCBI Full Name: | Histone-lysine N-methyltransferase SMYD3 |
| NCBI Synonym Full Names: | SET and MYND domain containing 3 |
| NCBI Official Symbol: | SMYD3 |
| NCBI Official Synonym Symbols: | KMT3E; ZMYND1; ZNFN3A1; bA74P14.1 |
| NCBI Protein Information: | histone-lysine N-methyltransferase SMYD3; bA74P14.1 (novel protein); zinc finger, MYND domain containing 1; SET and MYND domain-containing protein 3; zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing) |
| UniProt Protein Name: | Histone-lysine N-methyltransferase SMYD3 |
| UniProt Synonym Protein Names: | SET and MYND domain-containing protein 3; Zinc finger MYND domain-containing protein 1 |
| Protein Family: | Histone-lysine N-methyltransferase |
| UniProt Gene Name: | SMYD3 |
| UniProt Entry Name: | SMYD3_HUMAN |
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