Cell Biology Antibodies 3

Anti-SMPX Antibody (CAB13408)

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SKU:
CAB13408
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-SMPX Antibody
Antibody SKU:CAB13408
Antibody Size:20uL, 50uL, 100uL
Application:IF
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-88 of human SMPX (NP_055147.1).
Application:IF
Recommended Dilution:IF 1:50 - 1:200
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-88 of human SMPX (NP_055147.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MNMS KQPV SNVR AIQA NINI PMGA FRPG AGQP PRRK ECTP EVEE GVPP TSDE EKKP IPGA KKLP GPAV NLSE IQNI KSEL KYVP KAEQ
Gene ID:23676
Uniprot:Q9UHP9
Cellular Location:
Calculated MW:9kDa
Observed MW:
Synonyms:SMPX, DFN6, DFNX4
Background:This gene encodes a small protein that has no known functional domains. Mutations in this gene are a cause of X-linked deafness-4, and the encoded protein may play a role in the maintenance of inner ear cells subjected to mechanical stress. Alternatively spliced transcript variants have been observed for this gene.
UniProt Protein Function:SMPX: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair. Defects in SMPX are the cause of deafness X-linked type 4 (DFNX4). A non-syndromic form of sensorineural, progressive hearing loss with postlingual onset. In affected males, the auditory impairment affects initially high-frequency hearing. It later evolves to become severe to profound and affects all frequencies. Carrier females manifest moderate hearing impairment in the high frequencies. Belongs to the SMPX family.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: Xp22.1

Cellular Component: muscle tendon junction; costamere; M band; nucleus

Biological Process: striated muscle contraction

Disease: Deafness, X-linked 4

NCBI Summary:This gene encodes a small protein that has no known functional domains. Mutations in this gene are a cause of X-linked deafness-4, and the encoded protein may play a role in the maintenance of inner ear cells subjected to mechanical stress. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2011]
UniProt Code:Q9UHP9
NCBI GenInfo Identifier:239938852
NCBI Gene ID:23676
NCBI Accession:Q9UHP9.3
UniProt Secondary Accession:Q9UHP9,B1AWX2,
UniProt Related Accession:Q9UHP9
Molecular Weight:88
NCBI Full Name:Small muscular protein
NCBI Synonym Full Names:small muscle protein, X-linked
NCBI Official Symbol:SMPX  
NCBI Official Synonym Symbols:DFN6; DFNX4  
NCBI Protein Information:small muscular protein; deafness, X-linked 6, sensorineural; stretch-responsive skeletal muscle protein
UniProt Protein Name:Small muscular protein
UniProt Synonym Protein Names:Stretch-responsive skeletal muscle protein
Protein Family:Small muscular protein
UniProt Gene Name:SMPX  
UniProt Entry Name:SMPX_HUMAN
Anti-SMPX Antibody (CAB13408)Immunofluorescence analysis of HeLa cells using SMPX antibody (CAB13408). Blue: DAPI for nuclear staining.
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