Anti-SMOC1 Antibody (CAB20482)
- SKU:
- CAB20482
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- OAS
Description
| Product Name: | SMOC1 Rabbit pAb |
| Product Code: | CAB20482 |
| Size: | 50uL, 100uL |
| Synonyms: | OAS |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-250 of human SMOC1 (NP_071420.1). |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-250 of human SMOC1 (NP_071420.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 64093 |
| Uniprot: | Q9H4F8 |
| Calculated MW: | 48kDa |
| Observed MW: | 48KDa |
| UniProt Protein Function: | SMOC1: Plays essential roles in both eye and limb development. Probale regulator of osteoblast differentiation. Defects in SMOC1 are the cause of ophthalmoacromelic syndrome (OAS). A rare disorder presenting with anophthalmia or microphthalmia and limb anomalies. Limb malformations include fused 4th and 5th metacarpals and short 5th finger in hands, and olygodactyly in foot (four toes). Most patients have bilateral anophthalmia/ microphthalmia, but unilateral abnormality is also noted. Other malformations are rare, but venous or vertebral anomaly was recognized each in single cases. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 14q24.2 Molecular Function: protein binding Biological Process: eye development; limb development; regulation of osteoblast differentiation Disease: Microphthalmia With Limb Anomalies |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
| UniProt Code: | Q9H4F8 |
| NCBI GenInfo Identifier: | 38258649 |
| NCBI Gene ID: | 64093 |
| NCBI Accession: | Q9H4F8.1 |
| UniProt Secondary Accession: | Q9H4F8,Q96F78, A8K1S3, B2R7P5 |
| UniProt Related Accession: | Q9H4F8 |
| Molecular Weight: | 48,262 Da |
| NCBI Full Name: | SPARC-related modular calcium-binding protein 1 |
| NCBI Synonym Full Names: | SPARC related modular calcium binding 1 |
| NCBI Official Symbol: | SMOC1 |
| NCBI Official Synonym Symbols: | OAS |
| NCBI Protein Information: | SPARC-related modular calcium-binding protein 1 |
| UniProt Protein Name: | SPARC-related modular calcium-binding protein 1 |
| UniProt Synonym Protein Names: | Secreted modular calcium-binding protein 1; SMOC-1 |
| Protein Family: | SPARC-related modular calcium-binding protein |
| UniProt Gene Name: | SMOC1 |
| UniProt Entry Name: | SMOC1_HUMAN |
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