Name: Anti-SLU7 Antibody (CAB17614)
Brand: Cell Biology Antibodies 13
SKU: CAB17614
Availability: OutOfStock

Antibody Name:	Anti-SLU7 Antibody
Antibody SKU:	CAB17614
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SLU7 (NP_006416.3).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	Mouse testis, Mouse lung, Rat spleen, Rat lung

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SLU7 (NP_006416.3).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MSAT VVDA VNAA PLSG SKEM SLEE PKKM TRED WRKK KELE EQRK LGNA PAEV DEEG KDIN PHIP QYIS SVPW YIDP SKRP TLKH QRPQ PEKQ KQFS SSGE WYKR GVKE NSII TKYR KGAC ENCG AMTH KKKD CFER PRRV GAKF TGTN IAPD EHVQ PQLM FDYD GKRD RWNG YNPE EHMK IVEE YAKV DLAK RTLK AQKL QEEL ASGK LVEQ ANSP KHQW GEEE PNSQ MEKD HNSE DEDE DKYA DDID MPGQ NFDS KRRI TVRN LRIR EDIA KYLR NLDP NSAY YDPK TRAM RENP YANA
Gene ID:	10569
Uniprot:	O95391
Cellular Location:
Calculated MW:
Observed MW:	68kDa

Western blot - SLU7 Polyclonal Antibody (CAB17614)

Synonyms:

9G8, hSlu7, SLU7

Background:

Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008]

UniProt Protein Function:	SLU7: Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'- splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family.
UniProt Protein Details:	Protein type:Spliceosome; RNA splicing; RNA processing Chromosomal Location of Human Ortholog: 5q33.3 Cellular Component: cytoplasm; intracellular membrane-bound organelle; membrane; nuclear speck; nucleoplasm; nucleus; small nuclear ribonucleoprotein complex; spliceosome Molecular Function:pre-mRNA 3'-splice site binding; protein binding; second spliceosomal transesterification activity; zinc ion binding Biological Process: alternative nuclear mRNA splicing, via spliceosome; intracellular protein transport; mRNA 3'-end processing; mRNA export from nucleus; nuclear mRNA 3'-splice site recognition; nuclear mRNA splicing, via spliceosome; RNA export from nucleus; RNA splicing, via transesterification reactions; termination of RNA polymerase II transcription
NCBI Summary:	Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008]
UniProt Code:	O95391
NCBI GenInfo Identifier:	262527559
NCBI Gene ID:	10569
NCBI Accession:	O95391.2
UniProt Secondary Accession:	O95391,Q3LUJ0, Q3LUJ1, Q6RXQ5, Q96FM9, D3DQK2,
UniProt Related Accession:	O95391
Molecular Weight:	68,387 Da
NCBI Full Name:	Pre-mRNA-splicing factor SLU7
NCBI Synonym Full Names:	SLU7 homolog, splicing factor
NCBI Official Symbol:	SLU7
NCBI Official Synonym Symbols:	9G8; hSlu7
NCBI Protein Information:	pre-mRNA-splicing factor SLU7
UniProt Protein Name:	Pre-mRNA-splicing factor SLU7
Protein Family:	Pre-mRNA-splicing factor
UniProt Gene Name:	SLU7
UniProt Entry Name:	SLU7_HUMAN