Cell Biology Antibodies 4

Anti-SLMAP Antibody (CAB14367)

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SKU:
CAB14367
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-SLMAP Antibody
Antibody SKU:CAB14367
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 540-790 of human SLMAP (NP_009090.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse heart, Rat heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 540-790 of human SLMAP (NP_009090.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:IDTE NLRE EKDS EITS TRDE LLSA RDEI LLLH QAAA KVAS ERDT DIAS LQEE LKKV RAEL ERWR KAAS EYEK EITS LQNS FQLR CQQC EDQQ REEA TRLQ GELE KLRK EWNA LETE CHSL KREN VLLS SELQ RQEK ELHN SQKQ SLEL TSDL SILQ MSRK ELEN QVGS LKEQ HLRD SADL KTLL SKAE NQAK DVQK EYEK TQTV LSEL KLKF EMTE QEKQ SITD ELKQ CKNN LKLL REKG NNKP WPWM PML
Gene ID:7871
Uniprot:Q14BN4
Cellular Location:Cell membrane, Cytoplasm, Single-pass type IV membrane protein, centrosome, cytoskeleton, microtubule organizing center, sarcolemma
Calculated MW:31-57kDa/90-95kDa
Observed MW:45kDa
Synonyms:SLMAP, SLAP
Background:This gene encodes a component of a conserved striatin-interacting phosphatase and kinase complex. Striatin family complexes participate in a variety of cellular processes including signaling, cell cycle control, cell migration, Golgi assembly, and apoptosis. The protein encoded by this gene is a coiled-coil, tail-anchored membrane protein with a single C-terminal transmembrane domain that is posttranslationally inserted into membranes. Mutations in this gene are associated with Brugada syndrome, a cardiac channelopathy. Alternative splicing results in multiple transcript variants.
UniProt Code:Q14BN4
NCBI GenInfo Identifier:56550043
NCBI Gene ID:
NCBI Accession:NP_009090
Molecular Weight:
NCBI Full Name:sarcolemmal membrane-associated protein isoform b
UniProt Protein Name:Sarcolemmal membrane-associated protein
Protein Family:Sarcolemmal membrane-associated protein
UniProt Gene Name:SLMAP  
UniProt Entry Name:SLMAP_HUMAN
Anti-SLMAP Antibody (CAB14367)Western blot analysis of extracts of various cell lines, using SLMAP antibody (CAB14367) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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