Neuroscience

Anti-SLITRK4 Antibody (CAB12936)

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SKU:
CAB12936
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-SLITRK4 Antibody
Antibody SKU:CAB12936
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 648-837 of human SLITRK4 (NP_775101.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:Mouse liver, U-87MG, K-562
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 648-837 of human SLITRK4 (NP_775101.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KPTV KHEG LGNP DCGS MQLQ LRKH DHKT NKKD GLST EAFI PQTI EQMS KSHT CGLK ESET GFMF SDPP GQKV VMRN VADK EKDL LHVD TRKR LSTI DELD ELFP SRDS NVFI QNFL ESKK EYNS IGVS GFEI RYPE KQPD KKSK KSLI GGNH SKIV VEQR KSEY FELK AKLQ SSPD YLQV LEEQ TALN KI
Gene ID:139065
Uniprot:Q8IW52
Cellular Location:Membrane, Single-pass type I membrane protein
Calculated MW:94kDa
Observed MW:100kDa
Synonyms:SLITRK4
Background:This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:SLITRK4: Suppresses neurite outgrowth. Belongs to the SLITRK family.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq27.3

Cellular Component: integral to membrane

Biological Process: axonogenesis

NCBI Summary:This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Code:Q8IW52
NCBI GenInfo Identifier:46396931
NCBI Gene ID:139065
NCBI Accession:Q8IW52.1
UniProt Related Accession:Q8IW52
Molecular Weight:
NCBI Full Name:SLIT and NTRK-like protein 4
NCBI Synonym Full Names:SLIT and NTRK like family member 4
NCBI Official Symbol:SLITRK4  
NCBI Protein Information:SLIT and NTRK-like protein 4
UniProt Protein Name:SLIT and NTRK-like protein 4
UniProt Gene Name:SLITRK4  
UniProt Entry Name:SLIK4_HUMAN
Anti-SLITRK4 Antibody (CAB12936)Western blot analysis of extracts of various cell lines, using SLITRK4 antibody (CAB12936) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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system_update_altDatasheetHuman SLITRK4 Recombinant Protein SLIT and NTRK-like family proteins 4 is a member of the SLIT and NTRK-like family.This protein is characterized as an integral membrane