Name: Anti-SLC9A3R2 Antibody (CAB17591)
Brand: Cell Biology Antibodies 13
SKU: CAB17591
Availability: OutOfStock

Antibody Name:	Anti-SLC9A3R2 Antibody
Antibody SKU:	CAB17591
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human SLC9A3R2 (NP_001123484).

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human
Positive Samples:	HeLa

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human SLC9A3R2 (NP_001123484).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	DPGS PAAR SGLR AQDR LIEV NGQN VEGL RHAE VVAS IKAR EDEA RLLV VDPE TDEH FKRL RVTP TEEH VEGP LPSP VTNG TSPA QLNG GSAC SSRS DLPG SDKD TEDG SAWK QDPF QESG L
Gene ID:	9351
Uniprot:	Q15599
Cellular Location:
Calculated MW:
Observed MW:	50kDa

Western blot - SLC9A3R2 Polyclonal Antibody (CAB17591)

Synonyms:

E3KARP, NHE3RF2, NHERF-2, NHERF2, OCTS2, SIP-1, SIP1, TKA-1, SLC9A3R2

Background:

This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

UniProt Protein Function:	Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3 (PubMed:18829453). May also act as scaffold protein in the nucleus.
NCBI Summary:	This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
UniProt Code:	Q15599
NCBI GenInfo Identifier:	194018553
NCBI Gene ID:	9351
NCBI Accession:	NP_001123484.1
UniProt Secondary Accession:	Q15599,O00272, O00556, Q3KQY7, D3DU84, D3DU85, H3BSV6
UniProt Related Accession:	Q15599
Molecular Weight:	24,718 Da
NCBI Full Name:	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform a
NCBI Synonym Full Names:	SLC9A3 regulator 2
NCBI Official Symbol:	SLC9A3R2
NCBI Official Synonym Symbols:	SIP1; OCTS2; SIP-1; TKA-1; E3KARP; NHERF2; NHE3RF2; NHERF-2
NCBI Protein Information:	Na(+)/H(+) exchange regulatory cofactor NHE-RF2
UniProt Protein Name:	Na(+)/H(+) exchange regulatory cofactor NHE-RF2
UniProt Synonym Protein Names:	NHE3 kinase A regulatory protein E3KARP; SRY-interacting protein 1; SIP-1; Sodium-hydrogen exchanger regulatory factor 2; Solute carrier family 9 isoform A3 regulatory factor 2; Tyrosine kinase activator protein 1; TKA-1
UniProt Gene Name:	SLC9A3R2