Signal Transduction Antibodies 2
Anti-SLC7A6 Antibody (CAB17404)
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- SKU:
- CAB17404
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-SLC7A6 Antibody |
| Antibody SKU: | CAB17404 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 456-515 of human SLC7A6 (NP_003974.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 456-515 of human SLC7A6 (NP_003974.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GIAL SGVP FYFM GVYL PESR RPLF IRNV LAAI TRGT QQLC FCVL TELD VAEE KKDE RKTD |
| Gene ID: | 9057 |
| Uniprot: | Q92536 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | LAT3, LAT-2, y+LAT-2, SLC7A6 |
| Background: |
| UniProt Protein Function: | Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells. |
| UniProt Code: | Q92536 |
| NCBI GenInfo Identifier: | 115648022 |
| NCBI Gene ID: | 9057 |
| NCBI Accession: | NP_003974.3 |
| UniProt Secondary Accession: | Q92536,Q68DS4, Q7L1N3, |
| UniProt Related Accession: | Q92536 |
| Molecular Weight: | 56.8kDa |
| NCBI Full Name: | Y+L amino acid transporter 2 |
| NCBI Synonym Full Names: | solute carrier family 7 member 6 |
| NCBI Official Symbol: | SLC7A6 |
| NCBI Official Synonym Symbols: | LAT3; LAT-2; y+LAT-2 |
| NCBI Protein Information: | Y+L amino acid transporter 2 |
| UniProt Protein Name: | Y+L amino acid transporter 2 |
| UniProt Synonym Protein Names: | Cationic amino acid transporter, y+ system; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2 |
| UniProt Gene Name: | SLC7A6 |
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