Signal Transduction Antibodies 1
Anti-SLC7A1 Antibody (CAB14784)
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- SKU:
- CAB14784
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-SLC7A1 Antibody |
| Antibody SKU: | CAB14784 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human SLC7A1 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Raji, Jurkat, 22Rv1, Mouse testis, Rat brain, Rat liver |
| Immunogen: | A synthetic peptide of human SLC7A1 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6541 |
| Uniprot: | P30825 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 67kDa |
| Observed MW: | 68kDa |
| Synonyms: | SLC7A1, ATRC1, CAT-1, ERR, HCAT1, REC1L |
| Background: |
| UniProt Protein Function: | SLC7A1: High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. May also function as an ecotropic retroviral leukemia receptor. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family Chromosomal Location of Human Ortholog: 13q12.3 Cellular Component: membrane; integral to plasma membrane; plasma membrane Molecular Function:arginine transmembrane transporter activity Biological Process: transport; amino acid transport; arginine transport; ion transport; transmembrane transport |
| UniProt Code: | P30825 |
| NCBI GenInfo Identifier: | 1706185 |
| NCBI Gene ID: | 6541 |
| NCBI Accession: | P30825.1 |
| UniProt Secondary Accession: | P30825,Q5JR50, |
| UniProt Related Accession: | P30825 |
| Molecular Weight: | |
| NCBI Full Name: | High affinity cationic amino acid transporter 1 |
| NCBI Synonym Full Names: | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| NCBI Official Symbol: | SLC7A1 |
| NCBI Official Synonym Symbols: | ERR; ATRC1; CAT-1; HCAT1; REC1L |
| NCBI Protein Information: | high affinity cationic amino acid transporter 1; CAT1; ecotropic retroviral receptor; solute carrier family 7 member 1; amino acid transporter, cationic 1; ecotropic retrovirus receptor homolog; system Y+ basic amino acid transporter; ecotropic retroviral leukemia receptor homolog |
| UniProt Protein Name: | High affinity cationic amino acid transporter 1 |
| UniProt Synonym Protein Names: | Ecotropic retroviral leukemia receptor homolog; Ecotropic retrovirus receptor homolog; ERR; Solute carrier family 7 member 1; System Y+ basic amino acid transporter |
| Protein Family: | High affinity cationic amino acid transporter |
| UniProt Gene Name: | SLC7A1 |
| UniProt Entry Name: | CTR1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLC7A1 antibody (CAB14784) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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