Signal Transduction Antibodies 2
Anti-SLC6A9 Antibody (CAB16203)
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- SKU:
- CAB16203
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-SLC6A9 Antibody |
| Antibody SKU: | CAB16203 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SLC6A9 (NP_964012.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SH-SY5Y, K562, MCF7, mouse liver, C6, rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SLC6A9 (NP_964012.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSGG DTRA AIAR PRMA AAHG PVAP SSPE QVTL LPVQ RSFF LPPF SGAT PSTS LAES VLKV WHGA YNSG LLPQ LMAQ HSLA MAQN GAVP SEAT KRDQ NLKR GNWG NQIE FV |
| Gene ID: | 6536 |
| Uniprot: | P48067 |
| Cellular Location: | |
| Calculated MW: | 70kDa/72kDa/78kDa |
| Observed MW: | 78kDa |
| Synonyms: | SLC6A9, GCENSG, GLYT1 |
| Background: | The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by this gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft. |
| UniProt Protein Function: | Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission. |
| NCBI Summary: | The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by this gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft. [provided by RefSeq, Jun 2016] |
| UniProt Code: | P48067 |
| NCBI GenInfo Identifier: | 67782317 |
| NCBI Gene ID: | 6536 |
| NCBI Accession: | NP_001020016.1 |
| UniProt Secondary Accession: | P48067,Q5TAB8, Q5TAB9, Q5TAC0, A6NDH1, A6NII2, A6NNZ8 |
| UniProt Related Accession: | P48067 |
| Molecular Weight: | 72,482 Da |
| NCBI Full Name: | sodium- and chloride-dependent glycine transporter 1 isoform 3 |
| NCBI Synonym Full Names: | solute carrier family 6 member 9 |
| NCBI Official Symbol: | SLC6A9 |
| NCBI Official Synonym Symbols: | GLYT1; GCENSG |
| NCBI Protein Information: | sodium- and chloride-dependent glycine transporter 1 |
| UniProt Protein Name: | Sodium- and chloride-dependent glycine transporter 1 |
| UniProt Synonym Protein Names: | Solute carrier family 6 member 9 |
| UniProt Gene Name: | SLC6A9 |
 | Western blot analysis of extracts of various cell lines, using SLC6A9 antibody (CAB16203) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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