Neuroscience
Anti-SLC6A6 Antibody (CAB14783)
- SKU:
- CAB14783
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Neuroscience
Description
| Antibody Name: | Anti-SLC6A6 Antibody |
| Antibody SKU: | CAB14783 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-320 of human SLC6A6 (NP_001127839.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-320 of human SLC6A6 (NP_001127839.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LFQS FQKE LPWA HCNH SWNT PHCM EDTM RKNK SVWI TISS TNFT SPVI EFWE RNVL SLSP GIDH PGSL KWD |
| Gene ID: | 6533 |
| Uniprot: | P31641 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 22kDa/69kDa |
| Observed MW: | Refer to figures |
| Synonyms: | SLC6A6, TAUT |
| Background: | This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | TAUT: Required for the uptake of taurine. Transports both taurine and beta-alanine which requires sodium ions. Chloride ions are necessary for optimal uptake. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 3p25.1 Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane Molecular Function:neurotransmitter:sodium symporter activity; taurine:sodium symporter activity Biological Process: amino acid metabolic process; amino acid transport; ion transport; neurotransmitter transport; taurine transport; transmembrane transport; transport |
| NCBI Summary: | This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
| UniProt Code: | P31641 |
| NCBI GenInfo Identifier: | 1352535 |
| NCBI Gene ID: | 6533 |
| NCBI Accession: | P31641.2 |
| UniProt Secondary Accession: | P31641,Q9BRI2, Q9BXB0, B2RNU7, |
| UniProt Related Accession: | P31641,AAB25509 |
| Molecular Weight: | |
| NCBI Full Name: | Sodium- and chloride-dependent taurine transporter |
| NCBI Synonym Full Names: | solute carrier family 6 member 6 |
| NCBI Official Symbol: | SLC6A6 |
| NCBI Official Synonym Symbols: | TAUT |
| NCBI Protein Information: | sodium- and chloride-dependent taurine transporter |
| UniProt Protein Name: | Sodium- and chloride-dependent taurine transporter |
| UniProt Synonym Protein Names: | Solute carrier family 6 member 6 |
| Protein Family: | Sodium- and chloride-dependent taurine transporter |
| UniProt Gene Name: | SLC6A6 |
| UniProt Entry Name: | SC6A6_HUMAN |
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