Name: Anti-SLC6A14 Antibody (CAB10582)
Brand: Signal Transduction Antibodies 1
SKU: CAB10582
Availability: OutOfStock

Antibody Name:	Anti-SLC6A14 Antibody
Antibody SKU:	CAB10582
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 131-234 of human SLC6A14 (NP_009162.1).

Application:	WB
Recommended Dilution:	WB 1:1000 - 1:2000
Reactivity:	Human
Positive Samples:	A-549, MCF7, SGC-7901

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 131-234 of human SLC6A14 (NP_009162.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	YYNV IIAY SLYY MFAS FQSE LPWK NCSS WSDK NCSR SPIV THCN VSTV NKGI QEII QMNK SWVD INNF TCIN GSEI YQPG QLPS EQYW NKVA LQRS SGMN ETGV
Gene ID:	11254
Uniprot:	Q9UN76
Cellular Location:	Membrane, Multi-pass membrane protein
Calculated MW:	72kDa
Observed MW:	72kDa

Synonyms:	SLC6A14, BMIQ11
Background:	This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.

UniProt Protein Function:	SLC6A14: Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner. Genetic variations in SLC6A14 may be associated with obesity in some populations, as shown by significant differences in allele frequencies between obese and non-obese individuals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A14 subfamily.
UniProt Protein Details:	Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: Xq23 Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane; vesicle Molecular Function:amino acid transmembrane transporter activity; transporter activity Biological Process: amino acid metabolic process; amino acid transport; response to toxin; transport Disease: Body Mass Index Quantitative Trait Locus 11
NCBI Summary:	This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, May 2010]
UniProt Code:	Q9UN76
NCBI GenInfo Identifier:	41018156
NCBI Gene ID:	11254
NCBI Accession:	Q9UN76.1
UniProt Secondary Accession:	Q9UN76,Q5H942,
UniProt Related Accession:	Q9UN76
Molecular Weight:	72kDa
NCBI Full Name:	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
NCBI Synonym Full Names:	solute carrier family 6 member 14
NCBI Official Symbol:	SLC6A14
NCBI Official Synonym Symbols:	BMIQ11
NCBI Protein Information:	sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
UniProt Protein Name:	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
UniProt Synonym Protein Names:	Amino acid transporter ATB0+; Solute carrier family 6 member 14
Protein Family:	Sodium- and chloride-dependent neutral and basic amino acid transporter
UniProt Gene Name:	SLC6A14

Western blot analysis of extracts of various cell lines, using SLC6A14 antibody (CAB10582) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s.

Antibodies

SLC6A14 Antibody (PACO01820)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)