Signal Transduction Antibodies 2

Anti-SLC52A3 Antibody (CAB15935)

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SKU:
CAB15935
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-SLC52A3 Antibody
Antibody SKU:CAB15935
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC52A3 (NP_212134.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse kidney
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC52A3 (NP_212134.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:PGME APLS HLES RYLP AHFS PLVF FLLL SIMM ACCL VAFF VLQR QPRC WEAS VEDL LNDQ VTLH SIRP REEN DLGP AGTV DSSQ GQGY LEEK AAPC CPAH L
Gene ID:113278
Uniprot:Q9NQ40
Cellular Location:Apical cell membrane, Multi-pass membrane protein
Calculated MW:45kDa/50kDa
Observed MW:51kDa
Synonyms:SLC52A3, BVVLS, BVVLS1, C20orf54, RFT2, RFVT3, bA371L19.1, hRFT2
Background:This gene encodes a riboflavin transporter protein that is strongly expressed in the intestine and likely plays a role in intestinal absorption of riboflavin. The protein is predicted to have eleven transmembrane domains and a cell surface localization signal in the C-terminus. Mutations at this locus have been associated with Brown-Vialetto-Van Laere syndrome and Fazio-Londe disease.
UniProt Protein Function:Transporter for riboflavin, which must be obtained as a nutrient via intestinal absorption. Riboflavin transport is Na+-independent at low pH but significantly reduced by Na+ depletion under neutral pH conditions. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin, flavin mononucleotide (FMN), flavin adenine dinucleotide (FAD), by methylene blue, and to a lesser extent by amiloride.
NCBI Summary:This gene encodes a riboflavin transporter protein that is strongly expressed in the intestine and likely plays a role in intestinal absorption of riboflavin. The protein is predicted to have eleven transmembrane domains and a cell surface localization signal in the C-terminus. Mutations at this locus have been associated with Brown-Vialetto-Van Laere syndrome and Fazio-Londe disease. [provided by RefSeq, Mar 2012]
UniProt Code:Q9NQ40
NCBI GenInfo Identifier:156564359
NCBI Gene ID:113278
NCBI Accession:NP_212134.3
UniProt Secondary Accession:Q9NQ40,Q5W1A0, Q5W1A1, Q8NCL7, Q96GD5, A8K6P1,
UniProt Related Accession:Q9NQ40
Molecular Weight:45,043 Da
NCBI Full Name:solute carrier family 52, riboflavin transporter, member 3
NCBI Synonym Full Names:solute carrier family 52 member 3
NCBI Official Symbol:SLC52A3  
NCBI Official Synonym Symbols:RFT2; BVVLS; RFVT3; hRFT2; BVVLS1; C20orf54; bA371L19.1  
NCBI Protein Information:solute carrier family 52, riboflavin transporter, member 3
UniProt Protein Name:Solute carrier family 52, riboflavin transporter, member 3
UniProt Synonym Protein Names:Riboflavin transporter 2; hRFT2
Protein Family:Riboflavin transporter
UniProt Gene Name:SLC52A3  
Anti-SLC52A3 Antibody (CAB15935)Western blot analysis of extracts of mouse kidney, using SLC52A3 antibody (CAB15935) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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