Signal Transduction Antibodies 2
Anti-SLC52A3 Antibody (CAB15935)
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- SKU:
- CAB15935
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-SLC52A3 Antibody |
| Antibody SKU: | CAB15935 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC52A3 (NP_212134.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse kidney |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC52A3 (NP_212134.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PGME APLS HLES RYLP AHFS PLVF FLLL SIMM ACCL VAFF VLQR QPRC WEAS VEDL LNDQ VTLH SIRP REEN DLGP AGTV DSSQ GQGY LEEK AAPC CPAH L |
| Gene ID: | 113278 |
| Uniprot: | Q9NQ40 |
| Cellular Location: | Apical cell membrane, Multi-pass membrane protein |
| Calculated MW: | 45kDa/50kDa |
| Observed MW: | 51kDa |
| Synonyms: | SLC52A3, BVVLS, BVVLS1, C20orf54, RFT2, RFVT3, bA371L19.1, hRFT2 |
| Background: | This gene encodes a riboflavin transporter protein that is strongly expressed in the intestine and likely plays a role in intestinal absorption of riboflavin. The protein is predicted to have eleven transmembrane domains and a cell surface localization signal in the C-terminus. Mutations at this locus have been associated with Brown-Vialetto-Van Laere syndrome and Fazio-Londe disease. |
| UniProt Protein Function: | Transporter for riboflavin, which must be obtained as a nutrient via intestinal absorption. Riboflavin transport is Na+-independent at low pH but significantly reduced by Na+ depletion under neutral pH conditions. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin, flavin mononucleotide (FMN), flavin adenine dinucleotide (FAD), by methylene blue, and to a lesser extent by amiloride. |
| NCBI Summary: | This gene encodes a riboflavin transporter protein that is strongly expressed in the intestine and likely plays a role in intestinal absorption of riboflavin. The protein is predicted to have eleven transmembrane domains and a cell surface localization signal in the C-terminus. Mutations at this locus have been associated with Brown-Vialetto-Van Laere syndrome and Fazio-Londe disease. [provided by RefSeq, Mar 2012] |
| UniProt Code: | Q9NQ40 |
| NCBI GenInfo Identifier: | 156564359 |
| NCBI Gene ID: | 113278 |
| NCBI Accession: | NP_212134.3 |
| UniProt Secondary Accession: | Q9NQ40,Q5W1A0, Q5W1A1, Q8NCL7, Q96GD5, A8K6P1, |
| UniProt Related Accession: | Q9NQ40 |
| Molecular Weight: | 45,043 Da |
| NCBI Full Name: | solute carrier family 52, riboflavin transporter, member 3 |
| NCBI Synonym Full Names: | solute carrier family 52 member 3 |
| NCBI Official Symbol: | SLC52A3 |
| NCBI Official Synonym Symbols: | RFT2; BVVLS; RFVT3; hRFT2; BVVLS1; C20orf54; bA371L19.1 |
| NCBI Protein Information: | solute carrier family 52, riboflavin transporter, member 3 |
| UniProt Protein Name: | Solute carrier family 52, riboflavin transporter, member 3 |
| UniProt Synonym Protein Names: | Riboflavin transporter 2; hRFT2 |
| Protein Family: | Riboflavin transporter |
| UniProt Gene Name: | SLC52A3 |
 | Western blot analysis of extracts of mouse kidney, using SLC52A3 antibody (CAB15935) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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