Signal Transduction Antibodies 3

Anti-SLC4A2 Antibody (CAB7729)

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SKU:
CAB7729
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-SLC4A2 Antibody
Antibody SKU:CAB7729
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human SLC4A2 (NP_001186623.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:HeLa, A-549, Jurkat, HT-29
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human SLC4A2 (NP_001186623.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DDGG ASGR PLPK AQPG HRSY NLQE RRRI GSMT GAEQ ALLP RVPT DEIE AQTL ATAD LDLM KSHR FEDV PGVR RHLV RKNA KGST QSGR EGRE PGPT PRAR P
Gene ID:6522
Uniprot:P04920
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:135kDa/136kDa/137kDa
Observed MW:140kDa
Synonyms:SLC4A2, AE2, BND3L, EPB3L1, HKB3, NBND3
Background:This gene encodes a member of the anion exchanger family of membrane transport proteins. The encoded protein regulates intracellular pH, biliary bicarbonate secretion, and chloride uptake. Reduced expression of this gene may be associated with primary biliary cirrhosis (PBC) in human patients, while differential expression of this gene may be associated with malignant hepatocellular carcinoma, colon and gastric cancers.
UniProt Protein Function:Plasma membrane anion exchange protein of wide distribution.
NCBI Summary:This gene encodes a member of the anion exchanger family of membrane transport proteins. The encoded protein regulates intracellular pH, biliary bicarbonate secretion, and chloride uptake. Reduced expression of this gene may be associated with primary biliary cirrhosis (PBC) in human patients, while differential expression of this gene may be associated with malignant hepatocellular carcinoma, colon and gastric cancers. [provided by RefSeq, Nov 2016]
UniProt Code:P04920
NCBI GenInfo Identifier:314122220
NCBI Gene ID:6522
NCBI Accession:NP_001186621.1
UniProt Secondary Accession:P04920,Q45EY5, Q969L3, B2R6T0, B4DIT0, D3DX05, F8W682
UniProt Related Accession:P04920
Molecular Weight:136,247 Da
NCBI Full Name:anion exchange protein 2 isoform 1
NCBI Synonym Full Names:solute carrier family 4 member 2
NCBI Official Symbol:SLC4A2  
NCBI Official Synonym Symbols:AE2; HKB3; BND3L; NBND3; EPB3L1  
NCBI Protein Information:anion exchange protein 2
UniProt Protein Name:Anion exchange protein 2
UniProt Synonym Protein Names:Non-erythroid band 3-like protein; BND3L; Solute carrier family 4 member 2
UniProt Gene Name:SLC4A2  
Anti-SLC4A2 Antibody (CAB7729)Western blot analysis of extracts of various cell lines, using SLC4A2 antibody (CAB7729) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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