Cell Biology Antibodies 15
Anti-SLC47A2 Antibody (CAB18584)
- SKU:
- CAB18584
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-SLC47A2 Antibody |
Antibody SKU: | CAB18584 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of human SLC47A2. |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: |
Immunogen: | Recombinant protein of human SLC47A2. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 146802 |
Uniprot: | Q86VL8 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | Refer to figures |
Synonyms: | SLC47A2 |
Background: |
UniProt Protein Function: | SLC47A2: Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transporter; Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 17p11.2 Cellular Component: plasma membrane Molecular Function:drug transporter activity; drug:hydrogen antiporter activity Biological Process: multidrug transport; transmembrane transport |
NCBI Summary: | This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q86VL8 |
NCBI GenInfo Identifier: | 74727585 |
NCBI Gene ID: | 146802 |
NCBI Accession: | Q86VL8.1 |
UniProt Secondary Accession: | Q86VL8,Q63HJ9, Q8IV44, Q96NA1, A0JBX9, A0P8Z7, |
UniProt Related Accession: | Q86VL8 |
Molecular Weight: | 23,344 Da |
NCBI Full Name: | Multidrug and toxin extrusion protein 2 |
NCBI Synonym Full Names: | solute carrier family 47 member 2 |
NCBI Official Symbol: | SLC47A2 |
NCBI Official Synonym Symbols: | MATE2; MATE2K; MATE2-B; MATE2-K |
NCBI Protein Information: | multidrug and toxin extrusion protein 2 |
UniProt Protein Name: | Multidrug and toxin extrusion protein 2 |
UniProt Synonym Protein Names: | Kidney-specific H(+)/organic cation antiporter; Solute carrier family 47 member 2 |
Protein Family: | Multidrug and toxin extrusion protein |
UniProt Gene Name: | SLC47A2 |
UniProt Entry Name: | S47A2_HUMAN |