Signal Transduction Antibodies 2

Anti-SLC44A2 Antibody (CAB15178)

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SKU:
CAB15178
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-SLC44A2 Antibody
Antibody SKU:CAB15178
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC44A2 (NP_065161.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:SGC-7901, Mouse lung, Mouse thymus, Rat lung
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC44A2 (NP_065161.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AEVL QDGD CPAV LIPS KPLA RRCF PAIH AYKG VLMV GNET TYED GHGS RKNI TDLV EGAK KANG VLEA RQLA MRIF EDYT VSWY WIII GLVI AMAM SLLF I
Gene ID:57153
Uniprot:Q8IWA5
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:79kDa/80kDa
Observed MW:90kDa
Synonyms:SLC44A2, CTL2, PP1292
Background:
UniProt Protein Function:SLC44A2: Isoform 1, but not isoform 3, exhibits some choline transporter activity. Belongs to the CTL (choline transporter-like) family. 3 isoforms of the human protein are produced by alternative promoter.
UniProt Protein Details:

Protein type:Transporter; Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: lysosomal membrane; plasma membrane; integral to membrane

Molecular Function:signal transducer activity; choline transmembrane transporter activity

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylcholine biosynthetic process; choline transport; signal transduction; transmembrane transport

UniProt Code:Q8IWA5
NCBI GenInfo Identifier:222831612
NCBI Gene ID:57153
NCBI Accession:NP_065161.3
UniProt Related Accession:Q8IWA5
Molecular Weight:Predicted Molecular Mass: 23.9kDaAccurate Molecular Mass: 23kDa
NCBI Full Name:choline transporter-like protein 2 isoform 1
NCBI Synonym Full Names:solute carrier family 44 member 2
NCBI Official Symbol:SLC44A2  
NCBI Official Synonym Symbols:CTL2; PP1292  
NCBI Protein Information:choline transporter-like protein 2
UniProt Protein Name:Choline transporter-like protein 2
UniProt Synonym Protein Names:Solute carrier family 44 member 2
Protein Family:Chitinase-like protein
UniProt Gene Name:SLC44A2  
UniProt Entry Name:CTL2_HUMAN
Anti-SLC44A2 Antibody (CAB15178)Western blot analysis of extracts of various cell lines, using SLC44A2 antibody (CAB15178) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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