Name: Anti-SLC35A2 Antibody (CAB7233)
Brand: Signal Transduction Antibodies 3
SKU: CAB7233
Availability: OutOfStock

Antibody Name:	Anti-SLC35A2 Antibody
Antibody SKU:	CAB7233
Antibody Size:	20uL, 50uL, 100uL
Application:	IF
Reactivity:	Human
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human SLC35A2 (NP_001027460.1).

Application:	IF
Recommended Dilution:	IF 1:50 - 1:200
Reactivity:	Human
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-242 of human SLC35A2 (NP_001027460.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MAAV GAGG STAA PGPG AVSA GALE PGTA SAAH RRLK YISL AVLV VQNA SLIL SIRY ARTL PGDR FFAT TAVV MAEV LKGL TCLL LLFA QKRG NVKH LVLF LHEA VLVQ YVDT LKLA VPSL IYTL QNNL QYVA ISNL PAAT FQPS PRCS QSHS LCLC LRLR ALRS PAAS RAAT TTAA VFPP WRPH HGAL SAKV SAGE VRAG SNGG TQGR GTGV EGVG HLQD PSRH PPGP GSSG FGRW SFLP GH
Gene ID:	7355
Uniprot:	P78381
Cellular Location:	Golgi apparatus membrane, Multi-pass membrane protein
Calculated MW:	25kDa/34kDa/41kDa/44kDa
Observed MW:	Refer to figures

Synonyms:

SLC35A2, CDG2M, CDGX, UDP-Gal-Tr, UGALT, UGAT, UGT, UGT1, UGT2, UGTL

Background:

This gene encodes a member of the nucleotide-sugar transporter family. The encoded protein is a multi-pass membrane protein. It transports UDP-galactose from the cytosol into Golgi vesicles, where it serves as a glycosyl donor for the generation of glycans. Mutations in this gene cause congenital disorder of glycosylation type IIm (CDG2M). Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

UniProt Protein Function:	SLC35A2: Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function. Belongs to the nucleotide-sugar transporter family. SLC35A subfamily. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Transporter Chromosomal Location of Human Ortholog: Xp11.23-p11.22 Cellular Component: Golgi membrane; Golgi apparatus; integral to membrane; nucleus Molecular Function:protein binding; UDP-galactose transmembrane transporter activity; sugar:hydrogen ion symporter activity Biological Process: proton transport; galactose metabolic process; transmembrane transport; UDP-galactose transport Disease: Congenital Disorder Of Glycosylation, Type Iim
NCBI Summary:	This gene encodes a member of the nucleotide-sugar transporter family. The encoded protein is a multi-pass membrane protein. It transports UDP-galactose from the cytosol into Golgi vesicles, where it serves as a glycosyl donor for the generation of glycans. Mutations in this gene cause congenital disorder of glycosylation type IIm (CDG2M). Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
UniProt Code:	P78381
NCBI GenInfo Identifier:	2499228
NCBI Gene ID:	7355
NCBI Accession:	P78381.1
UniProt Secondary Accession:	P78381,Q8IV21, Q92553, A8K2L9, A8K9V1, B4DE11, B4DPT2 E7EW45,
UniProt Related Accession:	P78381
Molecular Weight:	396
NCBI Full Name:	UDP-galactose translocator
NCBI Synonym Full Names:	solute carrier family 35 (UDP-galactose transporter), member A2
NCBI Official Symbol:	SLC35A2
NCBI Official Synonym Symbols:	UGT; CDGX; UGAT; UGT1; UGT2; UGTL; CDG2M; UGALT; UDP-Gal-Tr
NCBI Protein Information:	UDP-galactose translocator; solute carrier family 35 (UDP-galactose transporter), member 2
UniProt Protein Name:	UDP-galactose translocator
UniProt Synonym Protein Names:	Solute carrier family 35 member A2; UDP-galactose transporter; UDP-Gal-Tr; UGT
Protein Family:	UDP-galactose translocator
UniProt Gene Name:	SLC35A2
UniProt Entry Name:	S35A2_HUMAN