Signal Transduction Antibodies 2

Anti-SLC34A3 Antibody (CAB16168)

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SKU:
CAB16168
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-SLC34A3 Antibody
Antibody SKU:CAB16168
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 210-320 of human SLC34A3 (NP_543153.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse brain, Mouse kidney, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 210-320 of human SLC34A3 (NP_543153.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ESAT ALLE RLSE LALG AASL TPRA QAPD ILKV LTKP LTHL IVQL DSDM IMSS ATGN ATNS SLIK HWCG TTGQ PTQE NSSC GAFG PCTE KNST APAD RLPC RHLF AGTE LTD
Gene ID:142680
Uniprot:Q8N130
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:63kDa
Observed MW:63kDa
Synonyms:SLC34A3, HHRH, NPTIIc
Background:This gene encodes a member of SLC34A transporter family of proteins, and is expressed primarily in the kidney. It is involved in transporting phosphate into cells via sodium cotransport in the renal brush border membrane, and contributes to the maintenance of inorganic phosphate concentration in the kidney. Mutations in this gene are associated with hereditary hypophosphatemic rickets with hypercalciuria. Alternatively spliced transcript variants varying in the 5' UTR have been found for this gene.
UniProt Protein Function:May be involved in actively transporting phosphate into cells via Na+ cotransport in the renal brush border membrane. Probably mediates 20-30% of the apical influx.
NCBI Summary:This gene encodes a member of SLC34A transporter family of proteins, and is expressed primarily in the kidney. It is involved in transporting phosphate into cells via sodium cotransport in the renal brush border membrane, and contributes to the maintenance of inorganic phosphate concentration in the kidney. Mutations in this gene are associated with hereditary hypophosphatemic rickets with hypercalciuria. Alternatively spliced transcript variants varying in the 5' UTR have been found for this gene.[provided by RefSeq, Apr 2010]
UniProt Code:Q8N130
NCBI GenInfo Identifier:293597523
NCBI Gene ID:142680
NCBI Accession:NP_001170787.1
UniProt Secondary Accession:Q8N130,A2BFA1,
UniProt Related Accession:Q8N130
Molecular Weight:65
NCBI Full Name:sodium-dependent phosphate transport protein 2C
NCBI Synonym Full Names:solute carrier family 34 member 3
NCBI Official Symbol:SLC34A3  
NCBI Official Synonym Symbols:HHRH; NPTIIc  
NCBI Protein Information:sodium-dependent phosphate transport protein 2C
UniProt Protein Name:Sodium-dependent phosphate transport protein 2C
UniProt Synonym Protein Names:Na(+)-dependent phosphate cotransporter 2C; Sodium/inorganic phosphate cotransporter IIC; Sodium/phosphate cotransporter 2C; Na(+)/Pi cotransporter 2C; NaPi-2c; Solute carrier family 34 member 3
UniProt Gene Name:SLC34A3  
Anti-SLC34A3 Antibody (CAB16168)Western blot analysis of extracts of various cell lines, using SLC34A3 antibody (CAB16168) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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