Signal Transduction Antibodies 2
Anti-SLC30A8 Antibody (CAB1679)
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- SKU:
- CAB1679
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-SLC30A8 Antibody |
| Antibody SKU: | CAB1679 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human SLC30A8 (NP_776250.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human SLC30A8 (NP_776250.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEFL ERTY LVND KAAK MYAF TLES VELQ QKPV NKDQ CPRE RPEE LESG GMYH CHSG SKPT EKGA NEYA YAKW KLC |
| Gene ID: | 169026 |
| Uniprot: | Q8IWU4 |
| Cellular Location: | Cell membrane, Cytoplasmic vesicle, Multi-pass membrane protein, secretory vesicle membrane |
| Calculated MW: | 35kDa/40kDa |
| Observed MW: | Refer to figures |
| Synonyms: | SLC30A8, ZNT8, ZnT-8 |
| Background: | The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene. |
| NCBI Summary: | The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010] |
| UniProt Code: | Q8IWU4 |
| NCBI GenInfo Identifier: | 64762489 |
| NCBI Gene ID: | 169026 |
| NCBI Accession: | NP_776250 |
| UniProt Related Accession: | Q8IWU4 |
| Molecular Weight: | |
| NCBI Full Name: | zinc transporter 8 isoform a |
| NCBI Synonym Full Names: | solute carrier family 30 member 8 |
| NCBI Official Symbol: | SLC30A8 |
| NCBI Official Synonym Symbols: | ZNT8; ZnT-8 |
| NCBI Protein Information: | zinc transporter 8 |
| UniProt Protein Name: | Zinc transporter 8 |
| UniProt Synonym Protein Names: | Solute carrier family 30 member 8 |
| UniProt Gene Name: | SLC30A8 |
| UniProt Entry Name: | ZNT8_HUMAN |
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